Molecular Immunogenetics Group Department of Genetics University of São Paulo - Ribeirão Preto Medical School
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Publications

Selected publications (2015 – 2020)

http://www.ncbi.nlm.nih.gov/pubmed?term=passos%20ga

Donate PB, .., Passos GA, .., Cunha FQ (2020) Cigarette smoke induces miR-132 packaged in Th17 exosomes that enhance osteoclastogenesis in inflammatory arthritis. Proc. Natl. Acad. Sci. USA (accepted for publication)

Oliveira EH, Assis AF, Speck-Hernandez CA, Duarte MJ, Passos GA (2020) Aire gene influences the length of the 3´UTR of mRNAs in medullary thymic epithelial cell. Frontiers in Immunology 11: 1039 doi: 10.3389/fimmu.2020.01039.

Passos GA (2019) Thymus Transcriptome and Cell Biology. (Springer-Nature Switzerland AG, ISBN 978-3-030-12039-9, DOI: 10.1007/978-3-030-12040-5), 390 pp, (Geraldo A. Passos, Editor).

Speck-Hernandez CA, Assis AF, Felicio RF, et al (2018) Aire disruption influences the medullary thymic epithelial cell transcriptome and interaction with thymocytes. Frontiers in Immunology  9: 964 doi: 10.3389/fimmu.2018.00964.

Assis AF, Li J, Donate PB, Dernowsek JA et al (2018) Predicted miRNA-mRNA-mediated posttranscriptional control associated with differences in cervical and thoracic thymus function. Molecular Immunology 99:39-52. doi: 10.1016/j.molimm.2018.04.003.

Passos GA, Speck-Hernandez CA, Assis AF et al (2018) Update on Aire and thymic negative selection. Immunology 153(1):10-20. doi: 10.1111/imm.12831.

Semeghini MS, de Azevedo FG, Fernandes RR et al (2018) Menopause transition promotes distinct modulation of mRNAs and miRNAs expression in calvaria and bone marrow osteoblastic cells. Cell Biology International 42:12-24. doi: 10.1002/cbin.10802.

Dernowsek JA, Pereira MC, Fornari TA, et al (2017) Posttranscriptional interaction between miR-450a-5p and miR-28-5p and STAT1 mRNA triggers osteoblastic differentiation of human mesenchymal stem cells. J Cell Biochem. 2017 Apr 13. doi: 10.1002/jcb.26060.

Oliveira EH, Macedo C, Collares CV et al (2016) Aire downregulation is associated with changes in the posttranscriptional control of peripheral tissue antigens in medullary thymic epithelial cells. Frontiers in Immunology 7: 526

Pezzi N, Assis AF, Cotrim-Sousa L et al (2016) Aire knockdown in medullary thymic epithelial cells affects Aire protein, deregulates cell adhesion genes and decreases thymocyte interaction. Molecular Immunology 77: 157-173

Passos GA, Mendes-da-Cruz DA, Oliveira EH (Editors) The Role of Aire, Micro-RNAs and Cell-Cell Interactions on Thymic Architecture and Induction of Tolerance. (eBook, 109 pp) Lausanne: Frontiers Media, 2016 ISBN: 978-2-88919-770-5

Passos GA, Mendes-da-Cruz DA, Oliveira EH. (2015) The Thymic Orchestration Involving Aire, miRNAs, and Cell-Cell Interactions during the Induction of Central Tolerance. Frontiers in Immunology 61: 352.

Fornari TA, Donate PB, Assis AF, Macedo C, Sakamoto-Hojo ET, Donadi EA, Passos GA (2015) Comprehensive Survey of miRNA-mRNA Interactions Reveals That Ccr7 and Cd247 (CD3 zeta) are Posttranscriptionally Controlled in Pancreas Infiltrating T Lymphocytes of Non-Obese Diabetic (NOD) Mice. Plos One 10(11): e0142688.

Macedo C, Oliveira EH, Almeida RS, Donate PB, Fornari TA, Pezzi N, Sakamoto-Hojo ET, Donadi EA, Passos GA. (2015) Aire-dependent peripheral tissue antigen mRNAs in mTEC cells feature networking refractoriness to microRNA interaction. Immunobiology 220: 93-102.

Xavier DJ, Takahashi P, Evangelista AF, Foss-Freitas MC, Foss MC, Donadi EA, Passos GA, Sakamoto-Hojo ET. (2015) Assessment of DNA damage and mRNA/miRNA transcriptional expression profiles in hyperglycemic versus non-hyperglycemic patients with type 2 diabetes mellitus. Mutation Research 776: 98-110.