{"id":1183,"date":"2021-10-28T14:37:07","date_gmt":"2021-10-28T17:37:07","guid":{"rendered":"https:\/\/sites.usp.br\/padrao8\/?page_id=1183"},"modified":"2024-11-05T14:36:09","modified_gmt":"2024-11-05T17:36:09","slug":"publications","status":"publish","type":"page","link":"https:\/\/sites.usp.br\/biomedchem\/publications\/","title":{"rendered":"PUBLICATIONS"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"1183\" class=\"elementor elementor-1183\" data-elementor-post-type=\"page\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-236d7a8 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"236d7a8\" data-element_type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-b465f21\" data-id=\"b465f21\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-b59cae7 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"b59cae7\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-576a6bb\" data-id=\"576a6bb\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-6943b93 elementor-widget elementor-widget-text-editor\" data-id=\"6943b93\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><b><i><span style=\"font-size: 14.0pt; mso-bidi-font-size: 12.0pt;\">Published Papers<\/span><\/i><\/b><\/p><p style=\"margin-left: .25in; text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1;\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-fareast-font-family: Arial; mso-bidi-font-family: Arial;\"><span style=\"font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-size-adjust: none; font-kerning: auto; font-optical-sizing: auto; font-feature-settings: normal; font-variation-settings: normal; font-variant-position: normal; font-stretch: normal; font-size: 7pt; line-height: normal; font-family: 'Times New Roman';\">\u00a0<\/span><\/span><!--[endif]--><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt;\">Valli, M.; D\u00f6ring, T.H.; Marx, E.; Ferreira, L.G.G.; Medina-Franco, J.L.; Andricopulo, A.D. Neglected Tropical Diseases: A Chemoinformatics Approach for the Use of Biodiversity in Anti-Trypanosomatid Drug Discovery. <i>Biomolecules<\/i>, 14(8), 1033, 2024. (<\/span><a href=\"https:\/\/doi.org\/10.3390\/biom14081033\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt;\">doi.org\/10.3390\/biom14081033<\/span><\/a><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt;\">)<\/span><\/p><p style=\"margin-left: .25in; text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1;\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt;\">G\u00f3mez-Garc\u00eda, A.; Prinz, A.K.; Jim\u00e9nez, D.A.A.; Zamora, W.J.; Barazorda-Ccahuana, H.L.; Ch\u00e1vez-Fumagalli, M.A.; Valli, M.; Andricopulo, A.D.; Bolzani, V.S.; Olmedo, D.A.; Sol\u00eds, P.N.; N\u00fa\u00f1ez, M.J.; P\u00e9rez, J.R.R.; S\u00e1nchez, H.A.V.; Hern\u00e1ndez, H.F.C.; Martinez, O.M.M.; Koch, O.; Medina-Franco, J.L. Updating and profiling the natural product-likeness of Latin American compound libraries. <i>Molecular Informatics<\/i>, 43:e202400052, 2024. (<\/span><a href=\"https:\/\/doi.org\/10.1002\/minf.202400052\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-weight: bold;\">doi.org\/10.1002\/minf.202400052<\/span><\/a><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt;\">)<\/span><\/p><p style=\"margin-left: .25in; text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1;\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt;\">Dias, L.C.; Espinoza-Ch\u00e1vez, R.M.; Rezende J\u00fanior, C.O.; de Souza, M.L.; Chelucci, R.C.; Michelan-Duarte, S.; Ferreira, L.L.G.; Valli, M.; de Oliveira, A.S.; Andricopulo, A.D. Structure-Metabolism Relationships of benzimidazole derivatives with anti-Trypanosoma cruzi activity for Chagas disease. <i>ChemMedChem<\/i>, e202400293, 2024. (<\/span><a href=\"https:\/\/doi.org\/10.1002\/cmdc.202400293\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-weight: bold;\">doi.org\/10.1002\/cmdc.202400293<\/span><\/a><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt;\">)<\/span><\/p><p style=\"margin-left: .25in; text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1;\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt;\">Fernandes, P.O.; Dias, A.L.T.; dos Santos J\u00fanior, V.S.; Serafim, M.S.M.; Sousa, Y.V.; Monteiro, G.C.; Coutinho, I.D.; Valli, M.; Verzola, M.M.S.A.; Ottoni, F.M.; P\u00e1dua, R.M.; Oda, F.B.; dos Santos, A.G.; Andricopulo, A.D.; Bolzani, V.S.; Mota, B.E.F.; Alves, R.J.; de Oliveira, R.B.; Kronenberger, T.; Maltarollo, V.G. Machine Learning-Based Virtual Screening of Antibacterial Agents against Methicillin-Susceptible and Resistant Staphylococcus aureus. <i>Journal of Chemical Information and Modeling<\/i>, 1(1), 2024. (<\/span><a title=\"DOI URL\" href=\"https:\/\/doi.org\/10.1021\/acs.jcim.4c00087\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt;\">doi.org\/10.1021\/acs.jcim.4c00087<\/span><\/a><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt;\">)<\/span><\/p><p style=\"margin-left: .25in; text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1;\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt;\">Wallach, I.; Bernard, D.; Nguyen, K.; Valli, M. et al. The Atomwise AIMS Program. AI is a viable alternative to high throughput screening: a 318-target study. <i>Scientific Reports<\/i>, 14(7526), 2024. (<\/span><a href=\"http:\/\/doi.org\/10.1038\/s41598-024-54655-z\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt;\">doi.org\/10.1038\/s41598-024-54655-z<\/span><\/a><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt;\">) <\/span><\/p><p style=\"margin-left: .25in; text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1;\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt;\">Espinoza-Ch\u00e1vez, R.M.; Rezende J\u00fanior, C.O.; de Souza, M.L.; Pauli, I.; Valli, M.; Ferreira, L.L.G.; Chelucci, R. C.; Michelan-Duarte, S.; da Silva, F.B.R.; Cruz, F.C.; de Oliveira, A.S.; Andricopulo, A.D.; Dias, L.C. Structure\u2013activity relationships of novel N-imidazoylpiperazines with potent anti-Trypanosoma cruzi activity. <i>Future Medicinal Chemistry<\/i>, 16(3), 2024. (<\/span><a href=\"https:\/\/doi.org\/10.4155\/fmc-2023-0185\"><span style=\"font-size: 10.5pt; mso-bidi-font-family: Arial; background: white;\">doi.org\/10.4155\/fmc-2023-0185<\/span><\/a><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt;\">)<\/span><\/p><p style=\"margin-left: .25in; text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1;\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt;\">G\u00f3mez-Garc\u00eda, A.; Jim\u00e9nez, D.A.A.; Zamora, W.J.; Barazorda-Ccahuana, H.L.; Ch\u00e1vez-Fumagalli, M.\u00c1.; Valli, M.; Andricopulo, A.D.; Bolzani, V.S.; Olmedo, D.A.; Sol\u00eds, P.N.; N\u00fa\u00f1ez, M.J.; P\u00e9rez, J.R.R.; S\u00e1nchez, H.A.V.; Hern\u00e1ndez, H.F.C.; Medina-Franco, J.L. Navigating the Chemical Space and Chemical Multiverse of a Unified Latin American Natural Product Database: LANaPDB.\u00a0<i>Pharmaceuticals<\/i>,\u00a030(16), 1388, 2023. (<\/span><a href=\"http:\/\/doi.org\/10.3390\/ph16101388\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt;\">doi.org\/10.3390\/ph16101388<\/span><\/a><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt;\">)<\/span><\/p><p style=\"margin-left: .25in; text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1;\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt;\">do Carmo, P.R.V; Marcacini, R.; Valli, M.; Silva-Silva, J.V.; Ferreira, L.L.G.; Pilon, A.C.; Bolzani, V.S.; Andricopulo, A.D.; Marx, E. Development of a novel chemoinformatics tool for natural products databases. <i>Future Drug Discovery<\/i>, 5(2), 2023. (<\/span><a href=\"http:\/\/doi.org\/10.4155\/fdd-2023-0007\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt;\">doi.org\/10.4155\/fdd-2023-0007<\/span><\/a><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt;\">).<\/span><\/p><p style=\"margin-left: .25in; text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1;\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt;\">Mannochio-Russo, H.; dos Santos, A.L.P.; Bueno, P.C.P.; Vieira, R.; Pinto, M.E.F.; Queiroz, S.A.S.; Dutra, L.A.; Felippe, L.G.; Batista, A.N.L.; Souza-Moreira, T.M.; Valli, M.; Medina, R.P.; Araujo, A.R.; Pilon, A.C.; Castro-Gamboa, I.; Cavalheiro, A.J.; Silva, D.H.S.; Furlan, M.; Bolzani<a>, V.S. Twenty-five years of natural products research in NuBBE. <i>Frontiers in Natural Products<\/i>, 2:1252092, 2023. (<\/a><\/span><a href=\"http:\/\/doi.org\/10.3389\/fntpr.2023.1252092\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt;\">doi.org\/10.3389\/fntpr.2023.1252092<\/span><\/a><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt;\">).<\/span><\/p><p style=\"margin-left: .25in; text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1;\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt;\">Alves, N.F.; Ribeiro, D.C.; Mannochio-Russo, H.; Queiroz, S.A.S.; Zocolo, G.J.; Bolzani, V.S.; Valli, M. Advanced Glycation End Products Inhibitors from <i>Talisia esculenta<\/i>. <i>Revista Virtual de Qu\u00edmica<\/i>, 15, 1, 2023. (<\/span><a href=\"http:\/\/doi.org\/10.21577\/1984-6835.20230019\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt;\">doi.org\/10.21577\/1984-6835.20230019<\/span><\/a><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt;\">).<\/span><\/p><p style=\"margin-left: .25in; text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1;\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt;\">Bueno, P.C.P.; Valli, M; Moreira, E.A.; Mannochio-Russo, H; Nascimento, V. Younger Researchers of the Brazilian Chemical Society: a network fostering representation, communication, and collaboration. <i>RSC Advances<\/i>, 13, 24331-24332, 2023. (<\/span><a href=\"http:\/\/doi.org\/10.1039\/D3RA90072J\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt;\">doi.org\/10.1039\/D3RA90072J<\/span><\/a><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt;\">).<\/span><\/p><p style=\"margin-left: .25in; text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1;\"><span lang=\"PT-BR\" style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-ansi-language: PT-BR;\">Teles, H.R.; Valli, M.; Ferreira, Leonardo L.G.; Andricopulo, A.D. Molecular Modeling, Virtual Screening and Molecular Dynamics for <i>Leishmania infantum<\/i> Methionyl-tRNA Synthetase. <i>The Journal of Physical Chemistry B<\/i>, 126, 51, 10834\u201310843, 2022. (<\/span><a href=\"http:\/\/doi.org\/10.1021\/acs.jpcb.2c05427\"><span lang=\"PT-BR\" style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-ansi-language: PT-BR;\">doi.org\/10.1021\/acs.jpcb.2c05427<\/span><\/a><span lang=\"PT-BR\" style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-ansi-language: PT-BR;\">).<\/span><\/p><p style=\"margin-left: .25in; text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1;\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt;\">Bajorath, J.; Ch\u00e1vez-Hern\u00e1ndez, A.L.; Duran-Frigola, M; Valli, M. et al. Chemoinformatics and artificial intelligence colloquium: progress and challenges in developing bioactive compounds. <i>Journal of Cheminformatics<\/i>, 14, 82, 2022. (<\/span><a href=\"https:\/\/doi.org\/10.1186\/s13321-022-00661-0\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt;\">doi.org\/10.1186\/s13321-022-00661-0<\/span><\/a><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt;\">).<\/span><\/p><p style=\"margin-left: .25in; text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1;\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt;\">Valli, M.; Souza, J.M.; Chelucci, R.C.; Biasetto, C.R.; Araujo, A.R.; Bolzani, V.S.; Andricopulo, A.D. Identification of natural cytochalasins as leads for neglected tropical diseases drug discovery. <i>PLoS One<\/i>, 17, e0275002, 2022 (<\/span><a href=\"http:\/\/doi.org\/10.1371\/journal.pone.0275002\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt;\">doi.org\/10.1371\/journal.pone.0275002<\/span><\/a><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt;\">).<\/span><\/p><p style=\"margin-left: .25in; text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1;\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt;\">Chipoline, I.C.; Brasil, B.F.A.B; Neto, J.S.S.; Valli, M.; Cenci, A.R.; Teixeira, K.F.; Zapp, D.; Brondani, D.; Ferreira, L.L.G.; Andricopulo, A.D.; de Oliveira, A.S.; Nascimento, V. Synthesis and investigation of the trypanocidal potential of novel 1,2,3-triazole-selenide hybrids. <i>European Journal of Medicinal Chemistry<\/i>, 243, 114687, 2022 (<\/span><a href=\"http:\/\/doi.org\/10.1016\/j.ejmech.2022.114687\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt;\">doi.org\/10.1016\/j.ejmech.2022.114687<\/span><\/a><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt;\">).<\/span><\/p><p style=\"margin-left: .25in; text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1;\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">Teles, H. R.; Ferreira, L. L. G.; Valli, M.; Andricopulo, A. D. Hierarchical Clustering and Target-Independent QSAR for Antileishmanial Oxazole and Oxadiazole Derivatives. <i>International Journal of Molecular Sciences<\/i>, 23(16), 8898, 2022 (<\/span><a href=\"http:\/\/doi.org\/10.3390\/ijms23168898\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">doi.org\/10.3390\/ijms23168898<\/span><\/a><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">).<\/span><\/p><p style=\"margin-left: .25in; text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1;\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">Oliveira, A.S.; Valli, M.; Ferreira, L.G.; Souza, J.M.; Meier,L.; Abreu, H.R.; Voltolini, B.G.; Llanes, L.C.; Nunes, R.J.; Braga, A.L.; Andricopulo, A.D. Novel Trypanocidal Thiophen-Chalcone Cruzain Inhibitors: Structure- and Ligand-Based Studies. <i>Future Medicinal Chemistry<\/i>, 14(11), 795-808, 2022 (<\/span><a href=\"https:\/\/doi.org\/10.4155\/fmc-2022-0013\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">doi.org\/10.4155\/fmc-2022-0013<\/span><\/a><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">).<\/span><\/p><p style=\"margin-left: .25in; text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1;\"><span lang=\"PT-BR\" style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-ansi-language: PT-BR; mso-bidi-font-weight: bold;\">Ntie-Kang, F.; Telukunta, K.K.; Fobofou, S.A.T.; Osamor, V.C.; Egieyeh, S. A.; Valli, M. et al. Computational Applications in Secondary Metabolite Discovery (CAiSMD): an online workshop. <i>Journal of cheminformatics<\/i>, 13(1), 1-11, 2021 (<\/span><a href=\"http:\/\/doi.org\/10.1186\/s13321-021-00546-8\"><span lang=\"PT-BR\" style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-ansi-language: PT-BR; mso-bidi-font-weight: bold;\">doi.org\/10.1186\/s13321-021-00546-8<\/span><\/a><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">).<\/span><\/p><p style=\"margin-left: .25in; text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1;\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">Zeraik, M. L.; Pauli, I.; Dutra, L. A.; Cruz, R. S.; Valli, M.; Paracatu, L. C.; de Faria, C. M. Q. G.; Ximenes, V.; Regasini, L. O.; Andricopulo, A. D.; Bolzani, V. S. Identification of a Prenyl Chalcone as a Competitive Lipoxygenase Inhibitor: Screening, Biochemical Evaluation and Molecular Modeling Studies. <i>Molecules<\/i>, 26(8), 2205, 2021 (<\/span><a href=\"http:\/\/doi.org\/10.3390\/molecules26082205\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">doi.org\/10.3390\/molecules26082205<\/span><\/a><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">).<\/span><\/p><p style=\"margin-left: .25in; text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1;\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">Valli, M. <\/span><span lang=\"PT-BR\" style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-ansi-language: PT-BR; mso-bidi-font-weight: bold; mso-bidi-font-style: italic;\">Planejamento de F\u00e1rmacos para a COVID-19 e a Inova\u00e7\u00e3o Farmac\u00eautica a partir de Produtos Naturais. <i>Revista Virtual de Qu\u00edmica<\/i>, 13(1), 1, 2021 (<\/span><a href=\"http:\/\/doi.org\/10.21577\/1984-6835.20210001\"><span lang=\"PT-BR\" style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-ansi-language: PT-BR; mso-bidi-font-weight: bold; mso-bidi-font-style: italic;\">doi.org\/10.21577\/1984-6835.20210001<\/span><\/a><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">).<\/span><\/p><p style=\"margin-left: .25in; text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1;\"><span lang=\"PT-BR\" style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-ansi-language: PT-BR; mso-bidi-font-weight: bold;\">Valli, M.; Atan\u00e1zio, L.C.V.; Monteiro, G.C.; Coelho, R.R.; Demarque, D.P.; Andricopulo, A.D.; Espindola, L.S.; Bolzani, V.S. The potential of biologically active Brazilian plant species as a strategy to search for molecular models for mosquito control. <i>Planta Medica<\/i>, 87(01\/02), 6-23, 2021<\/span><span lang=\"PT-BR\" style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-ansi-language: PT-BR; mso-bidi-font-weight: bold;\"> (<\/span><a href=\"http:\/\/doi.org\/10.1055\/a-1320-4610\"><span lang=\"PT-BR\" style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-ansi-language: PT-BR; mso-bidi-font-weight: bold;\">doi.org\/10.1055\/a-1320-4610<\/span><\/a><span lang=\"PT-BR\" style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-ansi-language: PT-BR; mso-bidi-font-weight: bold;\">)<\/span><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">.<\/span><\/p><p style=\"margin-left: .25in; text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1;\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">de Freitas, L.; Valli, M.; Dametto, A. C.; Pennacchi, P. C.; Andricopulo, A. D.; Maria-Engler, S. S.; Bolzani, V. S.<\/span> <span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">Advanced Glycation End Product Inhibition by Alkaloids from <i>Ocotea paranapiacabensis<\/i> for the Prevention of Skin Aging. <i>Journal of Natural Products<\/i>, 83(3), 649-656, 2020 <\/span><span lang=\"PT-BR\" style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-ansi-language: PT-BR; mso-bidi-font-weight: bold;\">(<\/span><a title=\"DOI URL\" href=\"https:\/\/doi.org\/10.1021\/acs.jnatprod.9b01083\"><span lang=\"PT-BR\" style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-ansi-language: PT-BR; mso-bidi-font-weight: bold;\">doi.org\/10.1021\/acs.jnatprod.9b01083<\/span><\/a><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">).<\/span><\/p><p style=\"margin-left: .25in; text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1;\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">Asse Jr., L. R.; Kronenberger, T.; Serafim, M. S. M.; Sousa, Y. V.; Franco, I. D.; Valli, M.; Bolzani, V. S.; Monteiro, G. C.; Prates, J. L. B.; Kroon, E. G.; Mota, B. E. F.; Ferreira, D. S.; Oliveira R. B.; Maltarollo, V. G. Virtual screening of antibacterial compounds by similarity search of Enoyl-ACP reductase (FabI) inhibitors. <i>Future Medicinal Chemistry<\/i>, 12(1), 51-68, 2020 <\/span><span lang=\"PT-BR\" style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-ansi-language: PT-BR; mso-bidi-font-weight: bold;\">(<\/span><a href=\"https:\/\/doi.org\/10.4155\/fmc-2019-0158\"><span lang=\"PT-BR\" style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-ansi-language: PT-BR; mso-bidi-font-weight: bold;\">doi.org\/10.4155\/fmc-2019-0158<\/span><\/a><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">).<\/span><\/p><p style=\"margin-left: .25in; text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1;\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">Valli, M.; Russo, H. M.; Pilon, A. C.; Pinto, M. E. F; Dias, N. B.; Freire, R. T.; Castro-Gamboa, I.; Bolzani, V. S. Computational Methods for NMR and MS for Structure Elucidation II: Database Resources and Advanced Methods, <i>Physical Sciences Reviews<\/i>, 4(11),<\/span> <span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">20180167, 2019 <\/span><span lang=\"PT-BR\" style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-ansi-language: PT-BR; mso-bidi-font-weight: bold;\">(<\/span><a href=\"https:\/\/doi.org\/10.1515\/psr-2018-0167\" target=\"_blank\" rel=\"noopener\"><span lang=\"PT-BR\" style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-ansi-language: PT-BR; mso-bidi-font-weight: bold;\">doi.org\/10.1515\/psr-2018-0167<\/span><\/a><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">).<\/span><\/p><p style=\"margin-left: .25in; text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1;\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">Valli, M.; Russo, H. M.; Pilon, A. C.; Pinto, M. E. F; Dias, N. B.; Freire, R. T.; Castro-Gamboa, I.; Bolzani, V. S. Computational Methods for NMR and MS for Structure Elucidation I: software for basic NMR, <i>Physical Sciences Reviews<\/i>, 4(10),<\/span> <span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">20180108, 2019 <\/span><span lang=\"PT-BR\" style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-ansi-language: PT-BR; mso-bidi-font-weight: bold;\">(<\/span><a href=\"https:\/\/doi.org\/10.1515\/psr-2018-0108\" target=\"_blank\" rel=\"noopener\"><span lang=\"PT-BR\" style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-ansi-language: PT-BR; mso-bidi-font-weight: bold;\">doi.org\/10.1515\/psr-2018-0108<\/span><\/a><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">).<\/span><\/p><p style=\"margin-left: .25in; text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1;\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">Koulouridi, E.; Valli, M.; Ntie-Kang, F.; Bolzani, V. S. A primer on natural product-based virtual screening. <i>Physical Sciences Reviews<\/i>, 4(6), <\/span><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-style: italic;\">20180105, 2019 <\/span><span lang=\"PT-BR\" style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-ansi-language: PT-BR; mso-bidi-font-weight: bold; mso-bidi-font-style: italic;\">(<\/span><a href=\"https:\/\/doi.org\/10.1515\/psr-2018-0105\" target=\"_blank\" rel=\"noopener\"><span lang=\"PT-BR\" style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-ansi-language: PT-BR; mso-bidi-font-weight: bold; mso-bidi-font-style: italic;\">doi.org\/10.1515\/psr-2018-0105<\/span><\/a><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-style: italic;\">).<\/span><\/p><p style=\"margin-left: .25in; text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1;\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">Valli, M.; Bolzani, V. Natural Products: Perspectives and Challenges for use of Brazilian Plant Species in the Bioeconomy. <i>Anais da Academia Brasileira de Ciencias<\/i>, 91(3), e20190208, 2019 <\/span><span lang=\"PT-BR\" style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-ansi-language: PT-BR; mso-bidi-font-weight: bold;\">(<\/span><a href=\"https:\/\/doi.org\/10.1590\/0001-3765201920190208\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">doi.org\/10.1590\/0001-3765201920190208<\/span><\/a><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">).<\/span><\/p><p style=\"margin-left: .25in; text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1;\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">Santos, N. C. F.; Valli, M.; Bolzani, V. S. A Brief Overview on Brazilian Women in Chemistry. <i>Pure and Applied Chemistry<\/i>, 91(4), 743-749, 2019 (<\/span><a href=\"https:\/\/doi.org\/10.1590\/0001-3765201920190208\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">doi.org\/10.1590\/0001-3765201920190208<\/span><\/a><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">).<\/span><\/p><p style=\"margin-left: .25in; text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1;\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">Batiga, S.; Valli, M.; Zeraik, M. L.; Fraige, K.; Leme, G. M.; Pitangui, N. S.; Almeida, A. M. F.; Michel, S.; Young, M. C. M.; Bolzani, V. S. Chemical composition and biological properties of <i>Ipomoea procumbens<\/i><\/span> <span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">. <i>Brazilian Journal of Pharmacognosy<\/i>, 29, 191\u2013197, 2019 (<\/span><a href=\"https:\/\/doi.org\/10.1016\/j.bjp.2018.08.010\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">doi.org\/10.1016\/j.bjp.2018.08.010<\/span><\/a><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">).<\/span><\/p><p style=\"margin-left: .25in; text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1;\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">Sald\u00edvar-Gonz\u00e1lez, F. I.; Valli, M.; Andricopulo, A. D.; Bolzani, V. S.; Medina-Franco, J. L. Chemical space and diversity of NuBBE database: A chemoinformatic characterization. <i>Journal of Chemical Information and Modeling<\/i>, 59, 74-85, 2019 (<\/span><a href=\"https:\/\/doi.org\/10.1021\/acs.jcim.8b00619\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold; mso-bidi-font-style: italic;\">doi.org\/10.1021\/acs.jcim.8b00619<\/span><\/a><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold; mso-bidi-font-style: italic;\">)<\/span><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">.<\/span><\/p><p style=\"margin-left: .25in; text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1;\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">Bosc, E.; Nastri, J.; Lefort, V.;\u00a0Valli, M.; Contiguiba, F.; Pioli, R.; Furlan, M.; Bolzani, V.S.; El Amri, C.; Reboud-Ravaux, M. Piperlongumine and some of its analogs inhibit selectively the human immunoproteasome over the constitutive proteasome. <i>Biochemical and Biophysical Research Communications<\/i>, 496, 3,\u00a0961-966, 2018 (<\/span><a href=\"https:\/\/doi.org\/10.1016\/j.bbrc.2018.01.100\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">doi.org\/10.1016\/j.bbrc.2018.01.100<\/span><\/a><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">).<\/span><\/p><p style=\"margin-left: .25in; text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1;\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">Valli, M.; Russo, H.; Bolzani, V. S. The potential contribution to bioeconomy of the natural products from Brazilian biodiversity. <i>Anais da Academia Brasileira de Ciencias<\/i>, 90, Issue 1, suppl.1, 63-778, 2018 (<\/span><a href=\"https:\/\/doi.org\/10.1590\/0001-3765201820170653\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">doi.org\/10.1590\/0001-3765201820170653<\/span><\/a><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">).<\/span><\/p><p style=\"margin-left: .25in; text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1;\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">Pilon, A. C.; Valli, M.; Dametto, A. C.; Pinto, M. E. F.; Freire, R. T.; Castro-Gamboa, I.; Andricopulo, A. D.; Bolzani, V. S. NuBBEDB: an updated database to uncover chemical and biological information from Brazilian biodiversity. <i>Scientific Reports<\/i>, 7, 7215, 2017 (<\/span><a href=\"https:\/\/doi.org\/10.1038\/s41598-017-07451-x\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">doi.org\/10.1038\/s41598-017-07451-x<\/span><\/a><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">).<\/span><\/p><p style=\"margin-left: .25in; text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1;\"><a><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">Valli, M.; Altei, W.; dos Santos, R.; De Lucca Jr., E.; Dessoy, M.; Pioli, R.; Cotinguiba, F.; Cachet, X.; Michel, S.; Furlan, M.; Dias, L.; Andricopulo, A.; Bolzani, V. Synthetic Analogue of the Natural Product Piperlongumine as a Potent Inhibitor of Breast Cancer Cell Line Migration. <i>Journal of the Brazilian Chemical Society<\/i>, 28, 475-484, 2017 (<\/span><\/a><a href=\"http:\/\/doi.org\/10.21577\/0103-5053.20160303\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">doi.org\/10.21577\/0103-5053.20160303<\/span><\/a><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">).<\/span><\/p><p style=\"margin-left: .25in; text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1;\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">Valli, M.; Young, M. C. M.; Bolzani, V. S. A Beleza Invis\u00edvel da Biodiversidade: O T\u00e1xon Rubiaceae. <i>Revista Virtual de Qu\u00edmica<\/i>, 8, 296-310, 2016 (<\/span><a href=\"http:\/\/doi.org\/10.5935\/1984-6835.20160020\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">doi.org\/10.5935\/1984-6835.20160020<\/span><\/a><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">).<\/span><\/p><p style=\"margin-left: .25in; text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1;\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">Valli, M.; Betti, A. H.;\u00a0Danuello, A.; Pivatto, M.; Centuri\u00e3o, F.; Antonio, C. B.; Rates, S. M. K.;\u00a0Bolzani, V. S. Pyridinic analog of the natural product (\u2212)-spectaline as potential adjuvant for the treatment of central nervous system disorders. <i>Bioorganic &amp; Medicinal Chemistry Letters<\/i>, 25(10), 2247-2250, 2015 (<\/span><a href=\"https:\/\/doi.org\/10.1016\/j.bmcl.2015.02.050\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">doi.org\/10.1016\/j.bmcl.2015.02.050<\/span><\/a><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">).<\/span><\/p><p style=\"margin-left: .25in; text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1;\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">Valli, M.; dos Santos<sup>, <\/sup>R.N.; Figueira, L.D.; Nakajima, C.H.; Andricopulo, A.D.; Bolzani, V.S. Development of a Natural Products Database from the Biodiversity of Brazil. <i>Journal of Natural Products<\/i>, 76(3)<i>,<\/i> 439-444, 2013 (<\/span><a href=\"https:\/\/doi.org\/10.1021\/np3006875\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">doi.org\/10.1021\/np3006875<\/span><\/a><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">).<\/span><\/p><p style=\"margin-left: .25in; text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1;\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">Valli, M.; Pivatto, M.; Danuello, A.; Silva, D.H.S.; Castro-Gamboa, I.; Cavalheiro, A.J.; Ara\u00fajo, A.R.; Furlan, M.; Lopes, M.N.; Bolzani, V.S. The Tropical Biodiversity: has it been a potential source of secondary metabolites useful for medicinal chemistry? <i>Qu\u00edmica Nova<\/i>, 35(11), 2278-2287, 2012 (<\/span><a href=\"https:\/\/doi.org\/10.1590\/S0100-40422012001100036\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">doi.org\/10.1590\/S0100-40422012001100036<\/span><\/a><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">).<\/span><\/p><p style=\"margin-left: .25in; text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1;\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt;\">Bolzani, V.S.; Valli, M.; Pivatto, M.; Viegas, Jr., C. Natural products from Brazilian biodiversity as a source of new models for medicinal chemistry. <i>Pure and Applied Chemistry<\/i>, 84(9), 1837-1846, 2012 (<\/span><a href=\"https:\/\/doi.org\/10.1351\/PAC-CON-12-01-11\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt;\">doi.org\/10.1351\/PAC-CON-12-01-11<\/span><\/a><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt;\">).<\/span><\/p><p style=\"margin-left: .25in; text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1;\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt;\">Valli, M.; Danuello, A.; Pivatto, M.; Salda\u00f1a, J.C.; Heinzen, H.; Dom\u00ednguez, L.; Campos, V.P.; Marqui, S.; Young, M.C.M; Silva, D.H.S.; Bolzani, V.S. Anticholinesterasic, Nematostatic and Anthelmintic Activities of Pyridinic and Pyrazinic Compounds. <i>Current Medicinal Chemistry<\/i>, 18(22), 3423-3430, 2011 (<\/span><a href=\"http:\/\/doi.org.10.2174\/092986711796504718\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt;\">doi.org.10.2174\/092986711796504718<\/span><\/a><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt;\">).<\/span><\/p><p style=\"line-height: normal;\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt;\">\u00a0<\/span><\/p><p style=\"line-height: normal; margin: 6.0pt 0in 6.0pt 0in;\"><b><i><span style=\"font-size: 14.0pt; mso-bidi-font-size: 12.0pt;\">Book Chapters<\/span><\/i><\/b><\/p><p style=\"margin-left: .25in; text-indent: -.25in; line-height: normal; mso-list: l1 level1 lfo2;\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">Valli, M.; Russo, H. M.; Pilon, A. C.; Pinto, M. E. F; Dias, N. B.; Freire, R. T.; Castro-Gamboa, I.; Bolzani, V. S. Chapter \u201cComputational Methods for NMR and MS for Structure Elucidation I: Software for Basic NMR\u201d, In: <i>Chemoinformatics of Natural Products<\/i>, editor Prof. Fidele Ntie-Kang. De Gruyter, ISBN (978-3-11-057935-2) published February 2020.<\/span><\/p><p style=\"margin-left: .25in; text-indent: -.25in; line-height: normal; mso-list: l1 level1 lfo2;\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">Valli, M.; Russo, H. M.; Pilon, A. C.; Pinto, M. E. F; Dias, N. B.; Freire, R. T.; Castro-Gamboa, I.; Bolzani, V. S. Chapter \u201cComputational Methods for NMR and MS for Structure Elucidation II: Database Resources and Advanced Methods\u201d, In: <i>Chemoinformatics of Natural Products<\/i>, editor Prof. Fidele Ntie-Kang. De Gruyter, ISBN (978-3-11-057935-2) published February 2020.<\/span><\/p><p style=\"margin-left: .25in; text-indent: -.25in; line-height: normal; mso-list: l1 level1 lfo2;\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">Koulouridi, E.; Valli, M.; Ntie-Kang, F.; Bolzani, V. S. Chapter \u201cA primer on natural product-based virtual screening\u201d, In: <i>Chemoinformatics of Natural Products<\/i>, editor Prof. Fidele Ntie-Kang. De Gruyter, ISBN (978-3-11-057935-2) published February 2020.<\/span><\/p><p style=\"margin-left: .25in; text-indent: -.25in; line-height: normal; mso-list: l1 level1 lfo2;\"><span style=\"font-size: 11.0pt; mso-bidi-font-family: Arial; color: black; background: white;\">Medina, R. P.; Biasetto, C. R.; Felippe, L. G.; Correia, L. C.; Valli, M.; Monteiro, A. F.; Araujo, A. R.;\u00a0Bolzani, V. S.;\u00a0Cavalheiro, A. J.;\u00a0Castro-Gamboa, I.; Furlan, M.; Silva, D. H. <span style=\"text-transform: uppercase;\">S<\/span><\/span><span style=\"font-size: 11.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">. Chapter <\/span><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">\u201cPlant Species from the Atlantic Forest Biome and Their Bioactive Constituents\u201d, In: <i>Brazilian Medicinal Plants<\/i> of the series Natural Products Chemistry of Global Plants, edited by Luzia V. Modolo; Mary Ann Foglio, CRC Press, ISNB (978-1-13-809375-1), published 25<sup>th<\/sup> November 2019.<\/span><\/p><p style=\"margin-left: .25in; text-indent: -.25in; line-height: normal; mso-list: l1 level1 lfo2;\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-family: Arial; mso-bidi-font-weight: bold;\">Flausino, Jr., O.; Valli, M; Bolzani, V.S. Biodiversidade brasileira: uma fonte potencial de agentes terap\u00eauticos ainda inexplorada. Book Chapter in \u2018<i>Qu\u00edmica de produtos naturais: novos f\u00e1rmacos e a moderna farmacognosia<\/i>\u2019 Ed: Rosendo A. Yunes e Valdir Cechinel Filho, 3rd ed., UNIVALI, published on 13th June 2012.<\/span><\/p><p style=\"line-height: normal;\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt;\">\u00a0<\/span><\/p><p style=\"line-height: normal; margin: 6.0pt 0in 6.0pt 0in;\"><b><i><span style=\"font-size: 14.0pt; mso-bidi-font-size: 12.0pt;\">General press contributions<\/span><\/i><\/b><\/p><p style=\"line-height: normal;\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-weight: bold;\">Andricopulo, A. D.; Valli, M. by Hallal, M. \u201cAnvisa autoriza estudo cl\u00ednico com proxalutamida no tratamento da covid-19\u201d. <i>O Estado de S\u00e3o Paulo<\/i>, 19<sup>th<\/sup> July 2021. <\/span><\/p><p style=\"line-height: normal;\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt;\">\u00a0<\/span><\/p><p style=\"line-height: normal; margin: 6.0pt 0in 6.0pt 0in;\"><b><i><span style=\"font-size: 14.0pt; mso-bidi-font-size: 12.0pt;\">Publicity article in newspaper\/electronic website<\/span><\/i><\/b><\/p><p style=\"margin-left: .25in; mso-add-space: auto; text-indent: -.25in; line-height: normal; mso-list: l2 level1 lfo3;\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-weight: bold;\">Moreira, E. A.; Valli, M. O papel da ci\u00eancia para alcan\u00e7ar os ODS no Brasil. JC Not\u00edcias &#8211; <i>Jornal da Ci\u00eancia<\/i>, 19<sup>th<\/sup> May 2022.<\/span><\/p><p style=\"margin-left: .25in; mso-add-space: auto; text-indent: -.25in; line-height: normal; mso-list: l2 level1 lfo3;\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-weight: bold;\">Moreira, E. A.; de Barros,H.R.; Valli, M. Deixar de investir em ci\u00eancia \u00e9 deixar de investir no Brasil. <i>JCNot\u00edcias<\/i>, 6704, 21<sup>st<\/sup> July 2021. <\/span><\/p><p style=\"margin-left: .25in; mso-add-space: auto; text-indent: -.25in; line-height: normal; mso-list: l2 level1 lfo3;\"><span style=\"font-size: 11.0pt; mso-bidi-font-size: 12.0pt; mso-bidi-font-weight: bold;\">Mannochio-Russo, H.; Nascimento,V.; de Barros,H.R.; Valli, M. Desafios e oportunidades para jovens pesquisadores brasileiros. <i>Jornal da Ci\u00eancia<\/i>, 14<sup>th<\/sup> November 2021<\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Published Papers \u00a0Valli, M.; D\u00f6ring, T.H.; Marx, E.; Ferreira, L.G.G.; Medina-Franco, J.L.; Andricopulo, A.D. Neglected Tropical Diseases: A Chemoinformatics Approach for the Use of Biodiversity in Anti-Trypanosomatid Drug Discovery. Biomolecules, 14(8), 1033, 2024. (doi.org\/10.3390\/biom14081033) G\u00f3mez-Garc\u00eda, A.; Prinz, A.K.; Jim\u00e9nez, D.A.A.; Zamora, W.J.; Barazorda-Ccahuana, H.L.; Ch\u00e1vez-Fumagalli, M.A.; Valli, M.; Andricopulo, A.D.; Bolzani, V.S.; Olmedo, D.A.; Sol\u00eds, [&hellip;]<\/p>\n","protected":false},"author":24350,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-1183","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/sites.usp.br\/biomedchem\/wp-json\/wp\/v2\/pages\/1183","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sites.usp.br\/biomedchem\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sites.usp.br\/biomedchem\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sites.usp.br\/biomedchem\/wp-json\/wp\/v2\/users\/24350"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.usp.br\/biomedchem\/wp-json\/wp\/v2\/comments?post=1183"}],"version-history":[{"count":4,"href":"https:\/\/sites.usp.br\/biomedchem\/wp-json\/wp\/v2\/pages\/1183\/revisions"}],"predecessor-version":[{"id":2987,"href":"https:\/\/sites.usp.br\/biomedchem\/wp-json\/wp\/v2\/pages\/1183\/revisions\/2987"}],"wp:attachment":[{"href":"https:\/\/sites.usp.br\/biomedchem\/wp-json\/wp\/v2\/media?parent=1183"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}