{"id":56,"date":"2022-09-07T19:09:49","date_gmt":"2022-09-07T21:09:49","guid":{"rendered":"http:\/\/localhost\/wordpress\/home\/"},"modified":"2025-03-24T09:52:00","modified_gmt":"2025-03-24T11:52:00","slug":"home","status":"publish","type":"page","link":"https:\/\/sites.usp.br\/cyngela\/","title":{"rendered":"Home"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"56\" class=\"elementor elementor-56\" data-elementor-post-type=\"page\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-04081e9 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"04081e9\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-30e0a82\" data-id=\"30e0a82\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-92bead8 elementor-widget elementor-widget-heading\" data-id=\"92bead8\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Our Scientific Mission<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-6917b7d elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"6917b7d\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-5a5992c\" data-id=\"5a5992c\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-50cec78 elementor-widget elementor-widget-text-editor\" data-id=\"50cec78\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>Our aim is to unravel the enigmatic roles of constitutive heterochromatin, particularly knobs, as essential components of genetic function and natural systems<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-2d324f3\" data-id=\"2d324f3\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-da2ca0f elementor-widget elementor-widget-image\" data-id=\"da2ca0f\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" src=\"https:\/\/sites.usp.br\/cyngela\/wp-content\/uploads\/sites\/1166\/2024\/12\/fgene-12-799681-g001.jpg\" title=\"fgene-12-799681-g001\" alt=\"fgene-12-799681-g001\" loading=\"lazy\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-deffe9e elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"deffe9e\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-4f8f572\" data-id=\"4f8f572\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-0db9fad elementor-widget elementor-widget-heading\" data-id=\"0db9fad\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Unraveling the Enigmatic Role of Heterochromatin in Organisms and Their Environment<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-e0ef54c elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"e0ef54c\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-62050b5\" data-id=\"62050b5\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-98a9dd2 elementor-widget elementor-widget-image\" data-id=\"98a9dd2\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" src=\"https:\/\/sites.usp.br\/cyngela\/wp-content\/uploads\/sites\/1166\/2024\/12\/paquiteno_milho.png\" title=\"paquiteno_milho\" alt=\"paquiteno_milho\" loading=\"lazy\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-81ab604\" data-id=\"81ab604\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-7912dbe elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"7912dbe\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-a50027a\" data-id=\"a50027a\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-68b3376 elementor-widget elementor-widget-text-editor\" data-id=\"68b3376\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>Our research group is devoted to the origin, evolution, physiological dynamic, structural organization, genome interaction, and responsiveness of the knob heterochromatins. We employed various approaches to address such complex questions, including molecular biology and genetics, bioinformatics, cytogenetics, cytogenomics, epigenetics, genomics, and chromatin analysis.\u00a0<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-9821889 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"9821889\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-9e8b969\" data-id=\"9e8b969\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-eae6bbd elementor-widget elementor-widget-heading\" data-id=\"eae6bbd\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">How we do it<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-ae2449b elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"ae2449b\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-3f7e28f\" data-id=\"3f7e28f\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-df94b29 elementor-widget elementor-widget-text-editor\" data-id=\"df94b29\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>\u25cb Molecular Biology and Genetics.<br \/>\u25cb Cytogenetics and Cytogenomics.<br \/>\u25cb Bioinformatics and Genomics.<br \/>\u25cb Epigenetics and Chromatin Analysis.<br \/>\u25cb CRISPR-Cas9 Genome Editing<br \/>\u25cb Plant Breeding &amp; Phenotypic Evaluation<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<div class=\"elementor-element elementor-element-72a49b5 elementor-widget elementor-widget-image\" data-id=\"72a49b5\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" src=\"https:\/\/sites.usp.br\/cyngela\/wp-content\/uploads\/sites\/1166\/2024\/12\/eaf0123a-956e-4b4c-81e6-2244a12dffa4.png\" title=\"moddotplot\" alt=\"moddotplot\" loading=\"lazy\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-050195c\" data-id=\"050195c\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-bc6f842 elementor-widget__width-initial elementor-widget elementor-widget-image\" data-id=\"bc6f842\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"1920\" height=\"2560\" src=\"https:\/\/sites.usp.br\/cyngela\/wp-content\/uploads\/sites\/1166\/2024\/12\/IMG_2923-1-scaled.jpg\" class=\"attachment-full size-full wp-image-1243\" alt=\"\" srcset=\"https:\/\/sites.usp.br\/cyngela\/wp-content\/uploads\/sites\/1166\/2024\/12\/IMG_2923-1-scaled.jpg 1920w, https:\/\/sites.usp.br\/cyngela\/wp-content\/uploads\/sites\/1166\/2024\/12\/IMG_2923-1-225x300.jpg 225w, https:\/\/sites.usp.br\/cyngela\/wp-content\/uploads\/sites\/1166\/2024\/12\/IMG_2923-1-768x1024.jpg 768w, https:\/\/sites.usp.br\/cyngela\/wp-content\/uploads\/sites\/1166\/2024\/12\/IMG_2923-1-1152x1536.jpg 1152w, https:\/\/sites.usp.br\/cyngela\/wp-content\/uploads\/sites\/1166\/2024\/12\/IMG_2923-1-1536x2048.jpg 1536w, https:\/\/sites.usp.br\/cyngela\/wp-content\/uploads\/sites\/1166\/2024\/12\/IMG_2923-1-400x533.jpg 400w\" sizes=\"(max-width: 1920px) 100vw, 1920px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-07d3845 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"07d3845\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-4539a7e\" data-id=\"4539a7e\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-eea7510 elementor-widget elementor-widget-html\" data-id=\"eea7510\" data-element_type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<a class=\"twitter-timeline\" data-lang=\"en\" data-height=\"500\" href=\"https:\/\/twitter.com\/Citogenetica?ref_src=twsrc%5Etfw\">Tweets by Citogenetica<\/a> <script async src=\"https:\/\/platform.twitter.com\/widgets.js\" charset=\"utf-8\"><\/script>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-93d054d\" data-id=\"93d054d\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-72bd078 elementor-widget elementor-widget-heading\" data-id=\"72bd078\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Vision<\/h3>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-27fd127 elementor-widget elementor-widget-text-editor\" data-id=\"27fd127\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>We see what nobody can see.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-90963d4 elementor-widget elementor-widget-heading\" data-id=\"90963d4\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Mission<\/h3>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-94694f0 elementor-widget elementor-widget-text-editor\" data-id=\"94694f0\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>To reveal the mysteries of the genome.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-817fa69 elementor-widget elementor-widget-heading\" data-id=\"817fa69\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Values<\/h3>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b1a291f elementor-widget elementor-widget-text-editor\" data-id=\"b1a291f\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>Truth above all and always, sincerity, team spirit, friendship, honesty, humbleness, loyalty, faithfulness, respect, and professionalism.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-b42e2a0 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"b42e2a0\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-ac18741\" data-id=\"ac18741\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-4608aff elementor-widget elementor-widget-text-editor\" data-id=\"4608aff\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>On the web since July 31, 2000.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-2c3667b elementor-hidden-desktop elementor-hidden-tablet elementor-hidden-mobile elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"2c3667b\" data-element_type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-53eae36\" data-id=\"53eae36\" data-element_type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-8409671 elementor-widget elementor-widget-heading\" data-id=\"8409671\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">About Us<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-16f2cba elementor-widget elementor-widget-text-editor\" data-id=\"16f2cba\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p class=\"custom-indent\">Emil Heitz first described Constitutive Heterochromatin at the same time as McClintock described maize chromosome structures called knobs. Despite their gene-silence nature, heterochromatin knobs were efficiently used to identify each one of the maize chromosomes and characterize landraces, inbred lines, and varieties. Knob variability among races of maize and its presence in relative species provided clues about the origin and domestication of this important crop. Later, the studies showed maize knob heterochromatin structures as S-phase late replicating, mainly composed of a highly-repetitive satellite DNA named K180 and by a second satellite DNA family named TR1, with the arrays interrupted by transposable elements invasion. Knob heterochromatin maintains its structure by epigenetic modification. Despite their gene-silence nature, knobs have been associated with latitude and altitude adaptation, flowering time, and other phenotypic traits. However, their direct contribution to phenotype has yet to be universally accepted or proven. The knob composition is responsible for the genome size differences in some groups of landraces. These knobs appear in gene-rich regions interfering with gene recombination and expression. In some exceptional cases, in the presence of the abnormal chromosome 10, which contains certain additional knobs, the regular knobs acquire neocentromere function, activating a meiotic drive system and allowing preferential segregation of the chromatids carrying these heterochromatic structures. All these features represent a transgression to the regular rules of the central dogma of molecular biology. Hence, the knobs are genome dark matter as a direct analogy to the universe\u2019s dark matter from physics.<\/p><p class=\"custom-indent\">Our research group is devoted to the origin, evolution, physiological dynamic, structural organization, genome interaction, and responsiveness of the knob heterochromatins. We employed various approaches to address such complex questions, including molecular biology and genetics, bioinformatics, cytogenetics, cytogenomics, epigenetics, genomics, and chromatin analysis. Thanks to knob diversity and using plant breeding strategies, we created a near-isogenic inbred line panel allowing Genome-Wide Association Studies [GWAS] to measure interactions with phenotypic traits through the isolation of heterochromatin effects. Other special inbred lines are in continued development, such as a knoblessness, a completely K180 empty line, that will be used to introgress specific knob positions and measure their responsiveness. A collection of wild species, called teosintes, maintained by our laboratory, represents the footsteps of the knobs heterochromatin evolution and has been used as a reference to understand the repetitive DNA sequence dynamics across time. We are also interested in the analysis of genomes sequenced from archeological samples addressing specifically the knob repetitive sequences. Our latest research focus centers on the utilization of genomic editing, employing the CRISPR-Cas9 system to induce specific knob modifications for investigating the repercussions of these alterations on their structure, dynamics, and behavior throughout the cell cycle, plant development, and potential implications for the phenotype. Our entire scientific endeavor is directed towards comprehending the role of these enigmatic genomic structures, known as constitutive heterochromatin, in the functioning of organismal genetics and as an integral component of the natural system.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-78ff55e elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"78ff55e\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-a9b967b\" data-id=\"a9b967b\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-00a22e3 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"00a22e3\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-1522a74\" data-id=\"1522a74\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-8f8c6fc elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"8f8c6fc\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-8b1948e\" data-id=\"8b1948e\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Our Scientific Mission Our aim is to unravel the enigmatic roles of constitutive heterochromatin, particularly knobs, as essential components of genetic function and natural systems Unraveling the Enigmatic Role of Heterochromatin in Organisms and Their Environment Our research group is devoted to the origin, evolution, physiological dynamic, structural organization, genome interaction, and responsiveness of the [&hellip;]<\/p>\n","protected":false},"author":23191,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-56","page","type-page","status-publish","hentry","entry"],"_links":{"self":[{"href":"https:\/\/sites.usp.br\/cyngela\/wp-json\/wp\/v2\/pages\/56","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sites.usp.br\/cyngela\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sites.usp.br\/cyngela\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sites.usp.br\/cyngela\/wp-json\/wp\/v2\/users\/23191"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.usp.br\/cyngela\/wp-json\/wp\/v2\/comments?post=56"}],"version-history":[{"count":4,"href":"https:\/\/sites.usp.br\/cyngela\/wp-json\/wp\/v2\/pages\/56\/revisions"}],"predecessor-version":[{"id":1272,"href":"https:\/\/sites.usp.br\/cyngela\/wp-json\/wp\/v2\/pages\/56\/revisions\/1272"}],"wp:attachment":[{"href":"https:\/\/sites.usp.br\/cyngela\/wp-json\/wp\/v2\/media?parent=56"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}