{"id":196,"date":"2022-02-08T15:55:37","date_gmt":"2022-02-08T17:55:37","guid":{"rendered":"https:\/\/sites.usp.br\/epigen\/?page_id=196"},"modified":"2022-04-01T18:01:03","modified_gmt":"2022-04-01T20:01:03","slug":"research","status":"publish","type":"page","link":"https:\/\/sites.usp.br\/epigen\/research\/","title":{"rendered":"Research"},"content":{"rendered":"<p><span style=\"color: #000000; font-size: 16pt; font-family: terminal, monaco, monospace;\"><strong>What we research<\/strong><\/span><\/p>\n<p><span style=\"color: #000000; font-family: terminal, monaco, monospace; font-size: 11pt;\">1- Sun exposure and human health.<\/span><\/p>\n<p><span style=\"color: #000000; font-family: terminal, monaco, monospace; font-size: 11pt;\">We are investigating several topics within this theme, including<\/span><\/p>\n<p><span style=\"color: #000000; font-family: terminal, monaco, monospace; font-size: 11pt;\"><span style=\"color: #000000; font-family: terminal, monaco, monospace; font-size: 11pt;\">\u00a0a. the relationship of pigmentation traits (i.e. skin, hair and eye colour, and tanning ability) with sun exposure preferences and practices<\/span><\/span><\/p>\n<p><span style=\"color: #000000; font-family: terminal, monaco, monospace; font-size: 11pt;\"><span style=\"color: #000000; font-family: terminal, monaco, monospace; font-size: 11pt;\">\u00a0b. the effects of sun exposure on dermatological traits (e.g. presence of naevi and freckles), biomarker circulating levels (vitamin D and serum folate) and disease (skin cancer and other conditions that may be positively or negatively affected by sunlight)<\/span><\/span><\/p>\n<p><span style=\"color: #000000; font-family: terminal, monaco, monospace; font-size: 11pt;\">\u00a0c. anthropometric, socioeconomic, cultural, mental health-related, and behavioural traits as determinants of sun exposure habits<\/span><\/p>\n<p><span style=\"color: #000000; font-family: terminal, monaco, monospace; font-size: 11pt;\">\u00a0d. genetic and epigenetic factors associated with sun exposure<\/span><\/p>\n<p><span style=\"color: #000000; font-family: terminal, monaco, monospace; font-size: 11pt;\">\u00a0e. tanning addiction, its predictors and outcomes<\/span><\/p>\n<p><span style=\"color: #000000; font-family: terminal, monaco, monospace; font-size: 11pt;\">\u00a0f. parental influence on children\u2019s sun exposure<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"color: #000000; font-family: terminal, monaco, monospace; font-size: 11pt;\">The role of DNA methylation as a potential mediator of genetic risk in skin cancer (EUROSKIN, 2021)<\/span><\/p>\n<p><iframe loading=\"lazy\" title=\"YouTube video player\" src=\"https:\/\/www.youtube.com\/embed\/URi_7jV81J4\" width=\"560\" height=\"315\" frameborder=\"0\" allowfullscreen=\"allowfullscreen\"><\/iframe><\/p>\n<p>&nbsp;<\/p>\n<p><a href=\"https:\/\/sites.usp.br\/epigen\/wp-content\/uploads\/sites\/950\/2022\/03\/abrasco.pdf\" target=\"_blank\" rel=\"noopener\"><span style=\"font-family: terminal, monaco, monospace;\"><span style=\"font-size: 11pt;\">Self-reported and genetically determined pigmentation affects tanning behaviour in UK youth (ABRASCO, 2021)<\/span><\/span><\/a><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"color: #000000; font-family: terminal, monaco, monospace; font-size: 11pt;\">2- The causal effects of modifiable environmental and lifestyle exposures on disease risk and other phenotypes using genetically-informed methods, particularly Mendelian randomization.<\/span><\/p>\n<p><span style=\"color: #000000; font-family: terminal, monaco, monospace; font-size: 11pt;\">3- The genetic background of admixed populations and its relationship with disease risk.<\/span><\/p>\n<p><span style=\"color: #000000; font-family: terminal, monaco, monospace; font-size: 11pt;\">4- Genetic risk and prognostic factors for cancer.<\/span><\/p>\n<p><span style=\"color: #000000; font-family: terminal, monaco, monospace; font-size: 11pt;\">Cancers that we work on are: breast, colorectal, prostate and skin cancer (melanoma and non-melanoma skin cancer).<\/span><\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>What we research 1- Sun exposure and human health. We are investigating several topics within this theme, including \u00a0a. the&#46;&#46;&#46;<\/p>\n","protected":false},"author":22756,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-196","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/sites.usp.br\/epigen\/wp-json\/wp\/v2\/pages\/196","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sites.usp.br\/epigen\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sites.usp.br\/epigen\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sites.usp.br\/epigen\/wp-json\/wp\/v2\/users\/22756"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.usp.br\/epigen\/wp-json\/wp\/v2\/comments?post=196"}],"version-history":[{"count":5,"href":"https:\/\/sites.usp.br\/epigen\/wp-json\/wp\/v2\/pages\/196\/revisions"}],"predecessor-version":[{"id":413,"href":"https:\/\/sites.usp.br\/epigen\/wp-json\/wp\/v2\/pages\/196\/revisions\/413"}],"wp:attachment":[{"href":"https:\/\/sites.usp.br\/epigen\/wp-json\/wp\/v2\/media?parent=196"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}