{"id":189,"date":"2023-11-20T11:55:54","date_gmt":"2023-11-20T13:55:54","guid":{"rendered":"https:\/\/sites.usp.br\/gnanobio\/?page_id=189"},"modified":"2026-03-28T18:16:16","modified_gmt":"2026-03-28T20:16:16","slug":"pesquisa-cientifica","status":"publish","type":"page","link":"https:\/\/sites.usp.br\/gnanobio\/pesquisa-cientifica\/","title":{"rendered":"Produ\u00e7\u00e3o cient\u00edfica"},"content":{"rendered":"<ul>\n<li lang=\"en\" data-ta=\"FullRTa-fullRecordtitle-0\"><a href=\"http:\/\/dx.doi.org\/10.1021\/acsomega.5c08442\">Chemosensitizer Effects of Coencapsulation of Curcumin and Cabazitaxel in Nanostructured Lipid Carriers in Glioblastoma Cells.<\/a><br \/>\nACS Omega; 2026.<\/li>\n<li lang=\"en\" data-ta=\"FullRTa-fullRecordtitle-0\"><a href=\"http:\/\/dx.doi.org\/10.1007\/s12668-025-02259-w\">Delivery Systems Containing Brazilian Red Propolis: Safety and Efficacy for Skin Wound Healing.<\/a><br \/>\nBionanoscience; 2026.<\/li>\n<li lang=\"en\" data-ta=\"FullRTa-fullRecordtitle-0\"><a href=\"http:\/\/dx.doi.org\/10.1016\/j.jddst.2025.106663\">Cytotoxic Potential of Polymeric Nanoparticles Loaded with Brazilian Red Propolis in Breast Cancer.<\/a><br \/>\nJOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY; 2025.<\/li>\n<li lang=\"en\" data-ta=\"FullRTa-fullRecordtitle-0\"><a href=\"http:\/\/dx.doi.org\/10.1021\/acsomega.4c08287\">Toxicity Assessment of Biogenic Gold Nanoparticles on Crop Seeds and Zebrafish Embryos: Implications for Agricultural and Aquatic Ecosystems. <\/a><br \/>\nACS Omega;\u00a02025.<\/li>\n<li lang=\"en\" data-ta=\"FullRTa-fullRecordtitle-0\"><a href=\"http:\/\/dx.doi.org\/10.1002\/cbdv.202402896\">Analgesic and Anti-inflammatory Effects of Free and Nanoencapsulated Green Propolis Extract from the Northeastern Brazilian Caatinga Biome.<\/a><br \/>\nCHEMISTRY &amp; BIODIVERSITY; 2025.<\/li>\n<li lang=\"en\" data-ta=\"FullRTa-fullRecordtitle-0\"><a href=\"http:\/\/dx.doi.org\/10.3390\/biomedicines13071643\">Brazilian Green Propolis Carried in Lipid-Based Nanostructures: A Potent Adjuvant Therapy to Non-Surgical Periodontal Treatment in the Management of Experimental Periodontitis.<\/a><br \/>\nBiomedicines; 2025.<\/li>\n<li lang=\"en\" data-ta=\"FullRTa-fullRecordtitle-0\"><a href=\"http:\/\/dx.doi.org\/10.1038\/s41598-025-05683-w\">Antiviral and anti-inflammatory efficacy of nanoencapsulated brazilian green propolis against SARS-CoV-2.<\/a><br \/>\nScientific Reports; 2025.<\/li>\n<li lang=\"en\" data-ta=\"FullRTa-fullRecordtitle-0\"><a href=\"http:\/\/dx.doi.org\/10.1002\/aoc.70350\">Cytotoxic Potential of Biogenic Gold Nanoparticles Functionalized With Brazilian Red Propolis in Prostate Cancer Cell Models.<\/a><br \/>\nAPPLIED ORGANOMETALLIC CHEMISTRY; 2025.<\/li>\n<li lang=\"en\" data-ta=\"FullRTa-fullRecordtitle-0\"><a href=\"http:\/\/dx.doi.org\/10.1016\/j.crbiot.2025.100277\">Biogenic silver nanoparticles produced by Trichoderma reesei inhibit SARS-CoV-2 infection, reduce lung viral load and ameliorate acute pulmonary inflammation.<\/a><br \/>\nCurrent Research In Biotechnology; 2025.<\/li>\n<li lang=\"en\" data-ta=\"FullRTa-fullRecordtitle-0\"><a href=\"http:\/\/dx.doi.org\/10.5650\/jos.ess2315\">Antibacterial Activity of Epigallocatechin-3-gallate (EGCG) Loaded Lipid-chitosan Hybrid Nanoparticle against Planktonic Microorganisms.<\/a><br \/>\nJournal of Oleo Science; 2024.<\/li>\n<li lang=\"en\" data-ta=\"FullRTa-fullRecordtitle-0\"><a href=\"http:\/\/dx.doi.org\/10.1016\/j.ijpharm.2024.124411\">Evaluation of in vivo and in vitro efficacy of solasonine\/solamargine-loaded lipid-polymer hybrid nanoparticles against bladder cancer.<\/a><br \/>\nINTERNATIONAL JOURNAL OF PHARMACEUTICS; 2024.<\/li>\n<li lang=\"en\" data-ta=\"FullRTa-fullRecordtitle-0\"><a href=\"http:\/\/dx.doi.org\/10.1016\/j.colsurfb.2024.114098\">Rational design of solid lipid-polymer hybrid nanoparticles: An innovative glycoalkaloids-carrier with potential for topical melanoma treatment.<\/a><br \/>\nCOLLOIDS AND SURFACES B-BIOINTERFACES; 2024.<\/li>\n<li lang=\"en\" data-ta=\"FullRTa-fullRecordtitle-0\"><a href=\"http:\/\/dx.doi.org\/10.3390\/pr12122856\">Antimicrobial, Antioxidant, and Anticancer Effects of Nanoencapsulated Brazilian Red Propolis Extract: Applications in Cancer Therapy.<\/a><br \/>\nPROCESSES; 2024.<\/li>\n<li lang=\"en\" data-ta=\"FullRTa-fullRecordtitle-0\"><a href=\"http:\/\/dx.doi.org\/10.3390\/ijms252212443\">Effectiveness of Local Use of Green Propolis-Loaded Lipid Nanoparticles as Adjuvant Therapy to Scaling and Root Planing in the Management of Periodontitis in Rats Treated with Zoledronate.<\/a><br \/>\nINTERNATIONAL JOURNAL OF MOLECULAR SCIENCES;\u00a02024.<\/li>\n<li lang=\"en\" data-ta=\"FullRTa-fullRecordtitle-0\"><a href=\"http:\/\/dx.doi.org\/10.1039\/d3ra08173g\">Naphthoquinone derivatives as potential immunomodulators: prospective for COVID-19 treatment.<\/a><br \/>\nRSC Advances; 2024.<\/li>\n<li lang=\"en\" data-ta=\"FullRTa-fullRecordtitle-0\"><a href=\"http:\/\/dx.doi.org\/10.1007\/s12602-024-10374-5\">\u00a0Characterization of a Peptidoglycan-Degrading Protein: Biochemical and Antimicrobial Characteristics, Antibiotic Synergism, and Delivery System Innovation.<\/a><br \/>\nProbiotics and Antimicrobial Proteins; 2024.<\/li>\n<li id=\"FullRTa-fullRecordtitle-0\" class=\"title text--large cdx-title\" lang=\"en\" style=\"text-align: justify;\" data-ta=\"FullRTa-fullRecordtitle-0\"><a href=\"https:\/\/doi.org\/10.1111\/ger.12672\">Action of chitosan-based solutions against a model four-species biofilm formed on cobalt-chromium and acrylic resin surfaces.<\/a><br \/>\nGERODONTOLOGY; 2023.<\/li>\n<li lang=\"en\" style=\"text-align: justify;\" data-ta=\"FullRTa-fullRecordtitle-0\"><a href=\"https:\/\/doi.org\/10.1093\/jpp\/rgad030\">Brazilian red propolis extract free and encapsulated into polymeric nanoparticles against ovarian cancer: formulation, characterisation and biological assays in 2D and 3D models\u00a0<\/a><br \/>\nJOURNAL OF PHARMACY AND PHARMACOLOGY;\u00a02023.<\/li>\n<li lang=\"en\" style=\"text-align: justify;\" data-ta=\"FullRTa-fullRecordtitle-0\"><a href=\"https:\/\/doi.org\/10.3390\/jfb14070374\">Solid Lipid-Polymer Hybrid Nanoplatform for Topical Delivery of siRNA: In Vitro Biological Activity and Permeation Studies.\u00a0<\/a><br \/>\nJournal Of Functional Biomaterials; 2023.<\/li>\n<li lang=\"en\" style=\"text-align: justify;\" data-ta=\"FullRTa-fullRecordtitle-0\"><a href=\"https:\/\/doi.org\/10.1016\/j.ejmech.2023.115451\">Design, synthesis and antitrypanosomatid activity of 2-nitroimidazole-3,5-disubstituded isoxazole compounds based on benznidazole.<\/a><br \/>\nEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY; 2023.<\/li>\n<li lang=\"en\" style=\"text-align: justify;\" data-ta=\"FullRTa-fullRecordtitle-0\"><a href=\"https:\/\/doi.org\/10.1002\/ptr.7910\">Comparing the activity of propolis-loaded nanoparticles or hydroethanolic extract on cytokine production by peripheral blood mononuclear cells.<\/a><br \/>\nPHYTOTHERAPY RESEARCH; 2023.<\/li>\n<li lang=\"en\" style=\"text-align: justify;\" data-ta=\"FullRTa-fullRecordtitle-0\"><a href=\"https:\/\/doi.org\/10.1016\/j.cbi.2022.110313\">Guttiferones: An insight into occurrence, biosynthesis, and their broad spectrum of pharmacological activities<\/a>.<br \/>\nCHEMICO-BIOLOGICAL INTERACTIONS; 2023.<\/li>\n<li lang=\"en\" style=\"text-align: justify;\" data-ta=\"FullRTa-fullRecordtitle-0\">\u00a0<a href=\"https:\/\/doi.org\/10.1155\/2022\/9004014\">Beta-caryophyllene as an antioxidant, anti-inflammatory and re-epithelialization activities in a rat skin wound excision model.<\/a><br \/>\nOXIDATIVE MEDICINE AND CELLULAR LONGEVITY (ONLINE); 2022.<\/li>\n<li lang=\"en\" style=\"text-align: justify;\" data-ta=\"FullRTa-fullRecordtitle-0\"><a href=\"https:\/\/rdcu.be\/dBDUb\">Efficacy of instillation of MB49 cells and thermoreversible polymeric gel in urothelial bladder carcinoma immunization.<\/a><br \/>\nLaboratory Animal Research; 2022.<\/li>\n<li lang=\"en\" style=\"text-align: justify;\" data-ta=\"FullRTa-fullRecordtitle-0\"><a href=\"https:\/\/doi.org\/10.1080\/01932691.2022.2116715\">Antioxidant and anti-tyrosinase activities of quercetin-loaded olive oil nanoemulsion as potential formulation for skin hyperpigmentation.<\/a><br \/>\nJOURNAL OF DISPERSION SCIENCE AND TECHNOLOGY;\u00a02022.<\/li>\n<li lang=\"en\" style=\"text-align: justify;\" data-ta=\"FullRTa-fullRecordtitle-0\"><a href=\"https:\/\/doi.org\/10.1038\/s41598-021-81281-w\">Biosynthesis and characterization of gold nanoparticles using Brazilian red propolis and evaluation of its antimicrobial and anticancer activities.<\/a><br \/>\nScientific Reports; 2021.<\/li>\n<li lang=\"en\" data-ta=\"FullRTa-fullRecordtitle-0\"><a href=\"http:\/\/dx.doi.org\/10.3390\/antibiotics10050569\">Phenothiazinium Photosensitizers Associated with Silver Nanoparticles in Enhancement of Antimicrobial Photodynamic Therapy.<\/a><br \/>\nANTIBIOTICS-BASEL; 2021.<\/li>\n<li lang=\"en\" data-ta=\"FullRTa-fullRecordtitle-0\"><a href=\"http:\/\/dx.doi.org\/10.1016\/j.archoralbio.2021.105148\">Effect on the inactivation of Metalloproteinases, Antimicrobial Activity and Adhesive Strength.<\/a><br \/>\nARCHIVES OF ORAL BIOLOGY; 2021<\/li>\n<li lang=\"en\" data-ta=\"FullRTa-fullRecordtitle-0\"><a href=\"http:\/\/dx.doi.org\/10.1007\/s12668-021-00872-z\">Effect of Chitosan-Coated Nanostructured Lipid Carrier on Escherichia coli Biofilms.<\/a><br \/>\nBioNanoScience;\u00a02021.<\/li>\n<li lang=\"en\" data-ta=\"FullRTa-fullRecordtitle-0\"><a href=\"http:\/\/dx.doi.org\/10.3389\/fbioe.2021.679128\">Hybrid nanoparticles as an efficient porphyrin delivery system for cancer cells to enhance photodynamic therapy.<\/a><br \/>\nFRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY; 2021.<\/li>\n<li lang=\"en\" data-ta=\"FullRTa-fullRecordtitle-0\">\u00a0<a href=\"http:\/\/dx.doi.org\/10.3390\/nano11113132\">Nanoparticle Systems for Cancer Phototherapy: An Overview.<\/a><br \/>\nNanomaterials; \u00a02021.<\/li>\n<li lang=\"en\" data-ta=\"FullRTa-fullRecordtitle-0\"><a href=\"http:\/\/dx.doi.org\/10.1016\/j.colsurfb.2020.111106\">Targeted uptake of folic acid-functionalized polymeric nanoparticles loading glycoalkaloidic extract in vitro and in vivo assays.<\/a><br \/>\nCOLLOIDS AND SURFACES B-BIOINTERFACES; 2020.<\/li>\n<li lang=\"en\" data-ta=\"FullRTa-fullRecordtitle-0\"><a href=\"http:\/\/dx.doi.org\/10.1016\/j.msec.2020.111460\">Cytotoxic and chemosensitizing effects of glycoalkaloidic extract on 2D and 3D models using RT4 and patient derived xenografts bladder cancer cells.<\/a><br \/>\nMaterials Science &amp; Engineering C-Materials for Biological Applications; 2020.<\/li>\n<li lang=\"en\" style=\"text-align: justify;\" data-ta=\"FullRTa-fullRecordtitle-0\"><a href=\"http:\/\/dx.doi.org\/10.1208\/s12249-020-01858-y\">Development of Photoprotective Formulations Containing Nanostructured Lipid Carriers: Sun Protection Factor, Physical-Mechanical and Sensorial Properties.<\/a><br \/>\nAAPS PHARMSCITECH; 2020.<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Chemosensitizer Effects of Coencapsulation of Curcumin and Cabazitaxel in Nanostructured Lipid Carriers in Glioblastoma Cells. ACS Omega; 2026. Delivery Systems Containing Brazilian Red Propolis: Safety and Efficacy for Skin Wound Healing. Bionanoscience; 2026. Cytotoxic Potential of Polymeric Nanoparticles Loaded with Brazilian Red Propolis in Breast Cancer. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY; 2025. Toxicity [&hellip;]<\/p>\n","protected":false},"author":23808,"featured_media":0,"parent":0,"menu_order":3,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-189","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/sites.usp.br\/gnanobio\/wp-json\/wp\/v2\/pages\/189","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sites.usp.br\/gnanobio\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sites.usp.br\/gnanobio\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sites.usp.br\/gnanobio\/wp-json\/wp\/v2\/users\/23808"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.usp.br\/gnanobio\/wp-json\/wp\/v2\/comments?post=189"}],"version-history":[{"count":4,"href":"https:\/\/sites.usp.br\/gnanobio\/wp-json\/wp\/v2\/pages\/189\/revisions"}],"predecessor-version":[{"id":416,"href":"https:\/\/sites.usp.br\/gnanobio\/wp-json\/wp\/v2\/pages\/189\/revisions\/416"}],"wp:attachment":[{"href":"https:\/\/sites.usp.br\/gnanobio\/wp-json\/wp\/v2\/media?parent=189"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}