{"id":829,"date":"2020-12-17T20:55:27","date_gmt":"2020-12-17T22:55:27","guid":{"rendered":"http:\/\/sites.usp.br\/rnpavc\/?page_id=829"},"modified":"2021-05-14T19:48:03","modified_gmt":"2021-05-14T21:48:03","slug":"publications-and-studies","status":"publish","type":"page","link":"https:\/\/sites.usp.br\/rnpavc\/language\/en\/publications-and-studies\/","title":{"rendered":"Trials and Publications"},"content":{"rendered":"<p>&nbsp;<\/p>\n<h3><b>Ongoing Trials\u00a0<\/b><\/h3>\n<p><strong>\u00a0Axiomatic\u00a0<\/strong><b>\u2013 <\/b><b>A Study on BMS-986177 for the Prevention of a Stroke in Patients Receiving Aspirin and Clopidogrel (AXIOMATIC-SSP)<\/b><\/p>\n<hr \/>\n<p><b>CHARM <strong>\u00a0<\/strong>\u2013<\/b><b>\u00a0Phase 3 Study to Evaluate the Efficacy and Safety of Intravenous BIIB093 (Glibenclamide) for Severe Cerebral Edema Following Large<\/b><\/p>\n<hr \/>\n<p style=\"text-align: justify;\"><a href=\"https:\/\/sites.usp.br\/rnpavc\/ethichs\/\"><b>ETHICHS <strong>\u00a0<\/strong>\u2013<\/b><\/a><b>\u00a0Esmolol for the Treatment of Hypertension after Intracerebral Hemorrhage Study\u00a0<\/b><\/p>\n<hr \/>\n<p style=\"text-align: justify;\"><b><a href=\"http:\/\/sites.usp.br\/rnpavc\/interact-3\/\">INTERACT-3<\/a> \u00a0<span style=\"font-weight: 400;\">\u2013 <\/span><\/b><b>The Third, Intensive Care Bundle With Blood Pressure Reduction in Acute Cerebral Hemorrhage Trial\u00a0<\/b><\/p>\n<hr \/>\n<p style=\"text-align: justify;\"><a href=\"https:\/\/sites.usp.br\/rnpavc\/588-2\/\"><b>OPTIMAL STROKE <span style=\"font-weight: 400;\">\u2013 <\/span><\/b><\/a><b>Optimal Blood Pressure for the prevenTIon of Major vAscuLar Events in Stroke Patients<\/b><\/p>\n<hr \/>\n<p style=\"text-align: justify;\"><strong>Resilient Direct TNK <span style=\"font-weight: 400;\"><b>\u2013 <\/b><\/span><\/strong><b>R<\/b><b>andomization to <\/b><b>E<\/b><b>ndoVascular Treatment Alone or Preceded by <\/b><b>S<\/b><b>ystemic Thrombolysis with Tenecteplase in Acute <\/b><b>I<\/b><b>schemic Stroke due to <\/b><b>L<\/b><b>arge <\/b><b>I<\/b><b>ntracranial V<\/b><b>E<\/b><b>ssel Occlusio<\/b><b>N<\/b> <b>T<\/b><b>rial \u2013<\/b><b>DIRECT<\/b><b> Thrombectomy vs. intravenous <\/b><b>TNK<\/b><b> plus thrombectomy\u00a0<\/b><\/p>\n<hr \/>\n<p style=\"text-align: justify;\"><b>Resilient Extend <strong><span style=\"font-weight: 400;\">\u2013 <\/span><\/strong>Randomization of Endovascular Treatment with Stent-retriever and\/or Thromboaspiration vs. Best Medical Therapy in Acute Ischemic Stroke due to Large VEssel OcclusioN Trial in the Extended Time Window (RESILIENT- Extend)<\/b><\/p>\n<hr \/>\n<p style=\"text-align: justify;\"><b><span style=\"font-weight: 400;\"><strong>Resilient Extend IV (in\u00edcio) \u2013 <\/strong><\/span><\/b><b>R<\/b><b>andomization to <\/b><b>E<\/b><b>xtend <\/b><b>S<\/b><b>troke <\/b><b>I<\/b><b>ntravenous Thrombo<\/b><b>L<\/b><b>ysis <\/b><b>I<\/b><b>n <\/b><b>E<\/b><b>volving <\/b><b>N<\/b><b>on-Large Vessel Occlusion with <\/b><b>T<\/b><b>NK (RESILIENT- Extend-IV)<\/b><\/p>\n<hr \/>\n<p style=\"text-align: justify;\"><b><a href=\"https:\/\/sites.usp.br\/rnpavc\/trident\/\">TRIDENT <\/a>\u00a0\u00a0<span style=\"font-weight: 400;\">\u2013 <\/span>Triple therapy prevention of Recurrent Intracerebral Disease EveNts Trial. <\/b><\/p>\n<hr \/>\n<p><span style=\"font-weight: 400;\"><strong>Tempo 2<\/strong> <b>\u2013<\/b>\u00a0<b>A Phase 3, Multi-Arm Multi-Stage Covariate-Adjusted Response-Adaptive Randomised Trial to Determine Optimal Early Mobility Training after Stroke (AVERT DOSE)<\/b><\/span><\/p>\n<hr \/>\n<p><span style=\"font-weight: 400;\"><strong>Avert-Dose <\/strong><b>\u2013 A trial to Determine the Optimal early mobility Training after StrokE<\/b><\/span><b>\u00a0<\/b><\/p>\n<hr \/>\n<p><strong>REGISTRO DE INDICADORES DE QUALIDADE DE AVC NO BRASIL<\/strong><\/p>\n<hr \/>\n<ul>\n<li style=\"list-style-type: none;\"><\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h3><b>Finished Trials and Respective Publications<\/b><\/h3>\n<p><a href=\"https:\/\/sites.usp.br\/rnpavc\/basics\/\"><b>BASICS <\/b><\/a><b>&#8211; <\/b><b>Basilar Artery International Cooperation Study<\/b><\/p>\n<hr \/>\n<p style=\"text-align: justify;\"><a href=\"https:\/\/sites.usp.br\/rnpavc\/bridge-stroke\/\"><b>BRIDGE-STROKE<\/b><\/a><b> <\/b><b>\u2013 <\/b><b>Brazi<\/b><b>lian inteRvention to Increase eviDence usaGe in practicE <\/b><b>\u2013 <\/b><b>Stroke<\/b><\/p>\n<hr \/>\n<p style=\"text-align: justify;\"><a href=\"https:\/\/sites.usp.br\/rnpavc\/enchanted\/\"><b>ENCHANTED <\/b><\/a><b>\u2013 <\/b><b>Enchanced Control of Hypertension and Thrombolysis Stroke Stud<\/b><b>y<\/b><\/p>\n<hr \/>\n<p style=\"text-align: justify;\"><a href=\"https:\/\/sites.usp.br\/rnpavc\/headpost\/\"><b>HeadPoST \u00a0<\/b><\/a><b>\u2013 \u00a0<\/b><b>Head Position in Stroke Trial<\/b><b>.\u00a0<\/b><\/p>\n<hr \/>\n<p><b><a href=\"https:\/\/sites.usp.br\/rnpavc\/resilient-2\/\">RESILIENT<\/a> <\/b><b>\u2013 <\/b><b><i>Randomization of EndoVascular Treatment with Solitaire<\/i><\/b><b> FR\u00ae vs. <\/b><b><i>Best Medical Therapy in Acute Ischemic Stroke due to Large VEssel OcclusioN Trial<\/i><\/b><b>)<\/b><\/p>\n<hr \/>\n<p style=\"text-align: justify;\"><a href=\"https:\/\/sites.usp.br\/rnpavc\/thales\/\"><b>THALES<\/b><\/a><b> &#8211; Acute STroke or Transient IscHaemic Attack Treated With TicAgreLor and ASA for PrEvention of Stroke and Death<\/b><\/p>\n<hr \/>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>&nbsp; Ongoing Trials\u00a0 \u00a0Axiomatic\u00a0\u2013 A Study on BMS-986177 for the Prevention of a Stroke in Patients Receiving Aspirin and Clopidogrel (AXIOMATIC-SSP) CHARM \u00a0\u2013\u00a0Phase 3 Study to Evaluate the Efficacy and Safety of Intravenous BIIB093 (Glibenclamide) for Severe Cerebral Edema Following Large ETHICHS \u00a0\u2013\u00a0Esmolol for the Treatment of Hypertension after Intracerebral Hemorrhage Study\u00a0 INTERACT-3 \u00a0\u2013 The<a href=\"https:\/\/sites.usp.br\/rnpavc\/language\/en\/publications-and-studies\/\">[&#8230;]<\/a><\/p>\n","protected":false},"author":906,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-829","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/sites.usp.br\/rnpavc\/wp-json\/wp\/v2\/pages\/829","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sites.usp.br\/rnpavc\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sites.usp.br\/rnpavc\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sites.usp.br\/rnpavc\/wp-json\/wp\/v2\/users\/906"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.usp.br\/rnpavc\/wp-json\/wp\/v2\/comments?post=829"}],"version-history":[{"count":4,"href":"https:\/\/sites.usp.br\/rnpavc\/wp-json\/wp\/v2\/pages\/829\/revisions"}],"predecessor-version":[{"id":1013,"href":"https:\/\/sites.usp.br\/rnpavc\/wp-json\/wp\/v2\/pages\/829\/revisions\/1013"}],"wp:attachment":[{"href":"https:\/\/sites.usp.br\/rnpavc\/wp-json\/wp\/v2\/media?parent=829"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}