Background. A promoter variant commonly found in sub-Saharan Africans and their descendants disrupts Duffy antigen (Fy) expression on erythrocytes, leading to the Fy-negative phenotype, and confers partial resistance to blood-stage Plasmodium vivaxinfection. In addition, the 125G->A substitution, rare in Africans, defines the Fya/Fyb polymorphism that can modulate vivax malaria risk in Amazonians. The combined effect […]

O EMME é um evento acadêmico interdisciplinar organizado pelo ICB e pelo IME, que abordou o tema da modelagem matemática aplicada à compreensão e análise da dinâmica de doenças infecciosas e outros fenômenos epidemiológicos. O evento foi realizado entre os dias 6 e 14 de outubro de 2025. Agradecemos a todos os envolvidos e, em […]

Background Brazil’s progress toward malaria elimination has stalled and 163,000 new cases (more than 80% caused by Plasmodium vivax) were recorded in the Brazilian Amazon in 2023. We hypothesize that human mobility continues to disperse parasites from hotspots to areas with decreasing endemicity. Methods We analyzed 5.5 million malaria case notifications between 2003 and 2023 […]

Mosquitos geneticamente modificados bloqueiam o ciclo de transmissão da malária Alteração genética reduz a capacidade de o Plasmodium falciparum se desenvolver no mosquito e bloqueia o ciclo de transmissão da doença, mostra estudo com participação da USP. Link: https://jornal.usp.br/ciencias/mosquitos-geneticamento-modificados-bloqueiam-o-ciclo-de-transmissao-da-malaria/.

✨ Italian dinner night! 🧑‍🍳 Homemade tortelli di zucca straight from the kitchen 😋!!!

Malaria remains a substantial global health challenge, causing approximately half a million deaths each year. The mosquito fibrinogen-related protein 1 (FREP1) is required for malaria parasites to infect the midgut epithelium. The naturally occurring FREP1Q allele has been reported to prevent parasite infection, while supporting essential physiological functions in the mosquito. We generate congenic strains […]

📍 O EMME é um evento acadêmico interdisciplinar que tem como foco o uso da modelagem matemática para compreender e analisar a dinâmica de doenças infecciosas e outros fenômenos epidemiológicos. 📌 A programação inclui grupos de estudo, palestras com especialistas renomados, roda de conversa e apresentações de trabalhos, promovendo a troca de experiências, o desenvolvimento de […]

Gene editing opens new path for controlling disease-spreading vectors Researchers from USP help develop a genetic system that reverses fruit fly resistance to insecticides, with minimal and self-limiting ecological impact.  

Prof. Dominik Heider (University of Münster) Date: February 25 Time: 2PM (BRT) Local: Anfiteatro Samuel Pessoa Anexo – ICB II – USP (Av. Prof. Lineu Prestes, 1374, São Paulo) Artificial Intelligence (AI) and machine learning (ML) are revolutionizing biomedical research by enabling advanced data-driven analyses across multiple domains, including omics sciences, clinical records, and medical […]

Vector mosquito control is an integral part of malaria control. The global emergence of insecticide resistance in malaria-transmitting Anophelines has become an impediment and has created an urgent need for novel mosquito control approaches. In our new paper in Science Advances, led by Chinmay Tikhe and George Dimopoulos from Johns Hopkins University, we show that a biopesticide […]