20. Serrano-Benitez A, Wells S, Drummond-Clarke L, Russo LC, Christopher Thomas J, Leal G, Farrow M, Edgerton JM, Balasubramanian S, Yang M, Frezza C, Gautam A, Brazina J, Burdova K, Hoch NC, Jackson SP, Caldecott KW. Unrepaired base excision repair intermediates in template DNA strands trigger replication fork collapse and PARP inhibitor sensitivity. The EMBO Journal. 2023 July 26. DOI: 10.15252/embj.2022113190
19. Di Lazzaro Filho R, Yamamoto GL, Silva TJ, Rocha LA , Linnenkamp BDW , Castro MAA, Bartholdi D, Schaller A, Leeb T, Kelmann S, Utagawa CY, Steiner CE, Steinmetz L, Honjo RS, Kim CA, Wang L, Abourjaili-Bilodeau R, Campeau PM, Warman M, Passos-Bueno MR, Hoch NC, Bertola DR. Biallelic variants in DNA2 cause poikiloderma with congenital cataracts and severe growth failure reminiscent of Rothmund-Thomson syndrome. Journal of Medical Genetics. 2023 April 13. DOI: 10.1136/jmg-2022-109119
18. Latancia MT, Moreno NC, Leandro GS, Ribeiro VC, Souza I, Vieira WKM, Bastos AU, Hoch NC, Rocha CRR, Menck CFM. DNA polymerase eta protects human cells against DNA damage induced by the tumor chemotherapeutic temozolomide. Mutation Research – Genetic Toxicology and Environmental Mutagenesis. 2022 May 5. DOI: 10.1016/j.mrgentox.2022.503498
17. Hoch NC. Host ADP-ribosylation and the SARS-CoV-2 macrodomain. Biochem Soc Trans. 2021 Aug 27;49(4):1711-1721. DOI: 10.1042/BST20201212
16. Russo LC, Tomasin R, Matos IA, Manucci AC, Sowa ST, Dale K, Caldecott KW, Lehtiö L, Schechtman D, Meotti FC, Bruni-Cardoso A, Hoch NC. The SARS-CoV-2 Nsp3 macrodomain reverses PARP9/DTX3L-dependent ADP-ribosylation induced by interferon signalling. J Biol Chem. 2021 Aug 3;297(3):101041. DOI: 10.1016/j.jbc.2021.101041
15. Lüscher B, Ahel I, Altmeyer M, Ashworth A, Bai P, Chang P, Cohen M, Corda D, Dantzer F, Daugherty MD, Dawson TM, Dawson VL, Deindl S, Fehr AR, Feijs KLH, Filippov DV, Gagné JP, Grimaldi G, Guettler S, Hoch NC, Hottiger MO, Korn P, Kraus WL, Ladurner A, Lehtiö L, Leung AKL, Lord CJ, Mangerich A, Matic I, Matthews J, Moldovan GL, Moss J, Natoli G, Nielsen ML, Niepel M, Nolte F, Pascal J, Paschal BM, Pawłowski K, Poirier GG, Smith S, Timinszky G, Wang ZQ, Yélamos J, Yu X, Zaja R, Ziegler M. ADP-ribosyltransferases, an update on function and nomenclature. FEBS J. 2021 Jul 29. DOI: 10.1111/febs.16142
14. King A, Hoch NC, McGregor NE, Sims NA, Smyth IM, and Heierhorst J (2019). Dynll1 is essential for development and promotes endochondral bone formation by regulating intraflagellar Dynein function in primary cilia. Hum Mol Genet: ddz083. DOI: 10.1093/hmg/ddz083
13. Hoch NC and Polo LM (2019). ADP-ribosylation: from molecular mechanisms to human disease. Genet Mol Biol. 43(1 suppl 1), e20190075. DOI: 10.1590/1678-4685-gmb-2019-0075
12. Baptista MS, Alves MJM, Arantes GM, Armelin HA, Augusto O, Baldini RL, Basseres DS, Bechara EJH, Bruni-Cardoso A, Chaimovich H, Colepicolo Neto P, Colli W, Cuccovia IM, Da-Silva AM, Di Mascio P, Farah SC, Ferreira C, Forti FL, Giordano RJ, Gomes SL, Gueiros Filho FJ, Hoch NC, Hotta CT, Labriola L, Lameu C, Machini MT, Malnic B, Marana SR, Medeiros MHG, Meotti FC, Miyamoto S, Oliveira CC, Souza-Pinto NC, Reis EM, Ronsein GE, Salinas RK, Schechtman D, Schreier S, Setubal JC, Sogayar MC, Souza GM, Terra WR, Truzzi DR, Ulrich H, Verjovski-Almeida S, Winck FV, Zingales B, and Kowaltowski AJ (2019). Where do we aspire to publish? A position paper on scientific communication in biochemistry and molecular biology. Braz J Med Biol Res. 52(9): e8935. DOI: 10.1590/1414-431×20198935
11. Liu R, King A, Hoch NC, Chang C, Kelly GL, Deans AJ, and Heierhorst J (2017). ASCIZ/ATMIN is dispensable for ATM signaling in response to replication stress. DNA Repair (Amst). 57: 29-34. DOI: 10.1016/j.dnarep.2017.06.022
10. Hoch NC, Hanzlikova H, Rulten SL, Tetreault M, Komulainen E, Ju L, Hornyak P, Zeng Z, Gittens W, Rey SA, Staras K, Mancini GM, McKinnon PJ, Wang ZQ, Wagner JD, Yoon G, and Caldecott KW (2017). XRCC1 mutation is associated with PARP1 hyperactivation and cerebellar ataxia. Nature. 541(7635): 87-91. DOI: 10.1038/nature20790
9. Hoch NC, Chen ES, Tsai MD, and Heierhorst J (2017). Quantitative Analysis of Yeast Checkpoint Protein Kinase Activity by Combined Mass Spectrometry Enzyme Assays. Methods Enzymol. 586: 143-164. DOI: 10.1016/bs.mie.2016.09.032
8. Breslin C, Mani RS, Fanta M, Hoch N, Weinfeld M, and Caldecott KW (2017). The Rev1 interacting region (RIR) motif in the scaffold protein XRCC1 mediates a low-affinity interaction with polynucleotide kinase/phosphatase (PNKP) during DNA single-strand break repair. J Biol Chem. 292(39): 16024-16031. DOI: 10.1074/jbc.M117.806638
7. Grundy GJ, Polo LM, Zeng Z, Rulten SL, Hoch NC, Paomephan P, Xu Y, Sweet SM, Thorne AW, Oliver AW, Matthews SJ, Pearl LH, and Caldecott KW (2016). PARP3 is a sensor of nicked nucleosomes and monoribosylates histone H2B(Glu2). Nat Commun. 7: 12404. DOI: 10.1038/ncomms12404
6. Hoch NC, Lai X, and Heierhorst J (2013). Genomic stability disorders: from budding yeast to humans. Front Biosci (Schol Ed). 5: 396-411. DOI: 10.2741/s379
5. Hoch NC, Chen ES, Buckland R, Wang SC, Fazio A, Hammet A, Pellicioli A, Chabes A, Tsai MD, and Heierhorst J (2013). Molecular basis of the essential s phase function of the rad53 checkpoint kinase. Mol Cell Biol. 33(16): 3202-13. DOI: 10.1128/MCB.00474-13
4. Chen ES, Hoch NC, Wang SC, Pellicioli A, Heierhorst J, and Tsai MD (2013). Use of quantitative mass spectrometric analysis to elucidate the mechanisms of phospho-priming and auto-activation of the checkpoint kinase Rad53 in vivo. Mol Cell Proteomics. DOI: 10.1074/mcp.M113.034058
3. Jurado S, Conlan LA, Baker EK, Ng JL, Tenis N, Hoch NC, Gleeson K, Smeets M, Izon D, and Heierhorst J (2012). ATM substrate Chk2-interacting Zn2+ finger (ASCIZ) Is a bi-functional transcriptional activator and feedback sensor in the regulation of dynein light chain (DYNLL1) expression. J Biol Chem. 287(5): 3156-64. DOI: 10.1074/jbc.M111.306019
2. Hoch NC, Santos RS, Rosa RM, Machado RM, Saffi J, Brendel M, and Henriques JA (2008). Allelism of Saccharomyces cerevisiae gene PSO10, involved in error-prone repair of psoralen-induced DNA damage, with SUMO ligase-encoding MMS21. Curr Genet. 53(6): 361-71. DOI: 10.1007/s00294-008-0192-z
1. Rosa RM, Hoch NC, Furtado GV, Saffi J, and Henriques JA (2007). DNA damage in tissues and organs of mice treated with diphenyl diselenide. Mutat Res. 633(1): 35-45. DOI: 10.1016/j.mrgentox.2007.05.006