Laboratory of Biochemistry and Immunology of Arthropods

Our research group develops research projects that aim to identify and characterize the molecular and cellular factors involved in the interactions among ticks, rickettsiae, the microbiota and the vertebrate host

HISTORY
The LBIA of the Department of Parasitology at ICB-USP was implemented in 1988 by professors Sirlei Daffre and Osvaldo Marinotti that introduced biochemical and molecular techniques for the study of different molecules of arachnids (spiders and ticks) and insects (mosquitoes and flies).

Ticks are ectoparasites that feed on the blood of vertebrate animals (hosts), being versatile vectors of a wide diversity of pathogens. Among the pathogens transmitted to humans by ticks, Rickettsia rickettsii, the etiological agent of Brazilian spotted fever, is one of the most lethal. R. rickettsii can be perpetuated for subsequent generations in tick populations of FMB endemic areas, as it presents transovarial transmission (transmission from the mother to the progeny), besides transstadial transmission (from one stage of the tick life cycle to another). Then, in addition to being vectors, ticks are reservoirs of the bacteria in nature.

The LBIA in the midia

Ciências para Todos: Carrapatos e sua ameaça

Existem 900 espécies de carrapatos, eles transmitem doenças muitas vezes letais para animais e o homem
Globoplay

Vacinas contra doenças causadas por carrapatos

Microrganismos causadores de doenças podem modular as respostas do sistema imune dos carrapatos

Revisão sobre sistema imune dos carrapatos

“Tick Immune System: What Is Known, the Interconnections, the Gaps, and the Challenges”