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FUGIO, LAIS BRIGLIADORI ; SILVA, GABRIEL ; FERRAZ, CAMILA LOPES ; TREVISAN, GLAUCE LUNARDELLI ; COELI-LACCHINI, FERNANDA BORCHERS ; GARCIA, CRISTIANA BERNADELLI ; SOUSA, LUCAS OLIVEIRA ; MALTA, TATHIANE MAISTRO ; GIL, CRISTIANE DAMAS ; Leopoldino, Andréia Machado . Accumulation of sphingosine kinase 2 protein induces malignant transformation in oral keratinocytes associated with stemness, autophagy, senescence, and proliferation. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, v. 1871, p. 119616, 2024.
TORRES, LIZETH ANDREA TORRES ; SILVA, GABRIEL ; ALVES, JOVELINA SAMARA FERREIRA ; USHIDA, TATIANE RESENDE ; POTENZA, JULIA ; GARCIA, CRISTIANA BERNADELLI ; SOUSA, LUCAS OLIVEIRA ; LOPES, NORBERTO PEPORINE ; ALMEIDA, LUCIANA OLIVEIRA ; Leopoldino, Andréia Machado . FTY720 increases paclitaxel efficacy in cisplatin-resistant oral squamous cell carcinoma. JOURNAL OF ORAL PATHOLOGY & MEDICINE, v.53(1), p. 42-52, 2024.
SILVA, GABRIEL DA ; MILAN, THAÍS MORÉ ; CHAGAS, PABLO SHIMAOKA ; TREVISAN, GLAUCE LUNARDELLI ; FERRAZ, CAMILA LOPES ; Leopoldino, Andréia Machado . SET protein as an epigenetics target. Epigenomics, v. 16(4), p. 249-257, 2023.
SILVA, G. ; KOWALSKI, L. P. ; MATOS, L. L. ; KULCSAR, M. ; Leopoldino, Andréia M. Profile of sphingolipid-related genes and its association with prognosis highlights sphingolipid metabolism in oral cancer. CANCER BIOMARKERS, v. 32, p. 49-63, 2021.
FUGIO, LAIS BRIGLIADORI ; COELI-LACCHINI, FERNANDA B. ; Leopoldino, Andréia Machado. Sphingolipids and Mitochondrial Dynamic. Cells, v. 9, p. 581, 2020.
OUCHIDA, A. T. ; TUDELLA, V. G. ; QUEIROZ, A. L. ; BRAUER, V.; CAVALCANTI NETO, M. P. ; Sousa, L.O.; Uyemura, S.A.; CURTI, C.; Andréia M Leopoldino. SET protein accumulation prevents cell death in head and neck squamous cell carcinoma through regulation of redox state and autophagy. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, v. 1866, p. 623-637, 2019.
LIMA, SANTIAGO ; TAKABE, KAZUAKI ; NEWTON, JASON ; SAURABH, KUMAR ; YOUNG, MEGAN M. ; LEOPOLDINO, ANDREIA MACHADO ; HAIT, NITAI C. ; ROBERTS, JANE L. ; WANG, HONG-GANG ; DENT, PAUL ; MILSTIEN, SHELDON ; BOOTH, LAURENCE ; SPIEGEL, SARAH. TP53 is required for BECN1- and ATG5-dependent cell death induced by sphingosine kinase 1 inhibition. Autophagy, v. 11, p. 1-16, 2018.
GOTO, RENATA NISHIDA ; SOBRAL, LAYS MARTIN ; SOUSA, LUCAS OLIVEIRA ; GARCIA, CRISTIANA BERNADELLI ; LOPES, NORBERTO PEPORINE ; MARÍN-PRIDA, JAVIER ; OCHOA-RODRÍGUEZ, ESTAEL ; VERDECIA-REYES, YAMILA ; PARDO-ANDREU, GILBERTO LÁZARO ; Curti, Carlos ; Leopoldino, Andréia Machado. Anti-cancer activity of a new dihydropyridine derivative, VdiE-2N, in head and neck squamous cell carcinoma. EUROPEAN JOURNAL OF PHARMACOLOGY, v. 819, p. 198-206, 2018.
Almeida, Luciana O. ; NETO, MARINALDO P. C. ; SOUSA, LUCAS O. ; TANNOUS, MARYNA A. ; Curti, Carlos ; Leopoldino, Andreia M. SET oncoprotein accumulation regulates transcription through DNA demethylation and histone hypoacetylation. OncoTarget, 8:26802-26818, 2017.
Sobral, Lays M. ; COLETTA, R. D. ; ALBERICI, L. C. ; CURTI, C. ; Leopoldino, Andreia M. . SET/I2PP2A overexpression induces phenotypic, molecular, and metabolic alterations in an oral keratinocyte cell line. FEBS Journal, p. x, 2017.
CAMPOS, L. ; RODRIGUEZ, Y. ; MACHADO LEOPOLDINO, A. ; HAIT, N. C. ; LOPEZ BERGAMI, P. ; CASTRO, M. ; SANCHEZ, E. ; MACEYKA, M. ; SPIEGEL, S. ; ALVAREZ, S. E. . Filamin A Expression Negatively Regulates Sphingosine-1-Phosphate-Induced NF- B Activation in Melanoma Cells by Inhibition of Akt Signaling. Molecular and Cellular Biology (Print), v. 36, p. 320-329, 2016.
SAYURI, C. M. ; ALMEIDA, L. O. ; GUIMARAES, D. M. ; MARTINS, M. D. ; PAPAGERAKIS, P. ; PAPAGERAKIS, S. ; LEOPOLDINO, A. M. ; CASTILHO, R. M. ; SQUARIZE, C. . PI3K-PTEN dysregulation leads to mTOR-driven upregulation of the core clock gene BMAL1 in normal and malignant epithelial cells. OncoTarget, p. xx, 2016.
Almeida, Luciana O. ; GOTO, RENATA N. ; NETO, MARINALDO P.C. ; SOUSA, LUCAS O. ; Curti, Carlos ; Leopoldino, Andréia M. SET overexpression in HEK293 cells regulates mitochondrial uncoupling proteins levels within a mitochondrial fission/reduced autophagic flux scenario. Biochemical and Biophysical Research Communications (Print), v. xx, p. xx, 2015
ALMEIDA, L. O. ; Garcia, C.B. ; SILVA, F. A. M.. ; CURTI, C. ; Leopoldino, Andréia M. Accumulated SET protein up-regulates and interacts with hnRNPK, increasing its binding to nucleic acids, the Bcl-xS repression, and cellular proliferation. Biochemical and Biophysical Research Communications (Print), p. xx, 2014.
SILVA, V. B. ; Leopoldino, Andréia M. ; Tomich CHPS . In Silico Bioisosteric Replacements of hnRNP K Ligands as Anticancer Lead Compounds. Current Physical Chemistry, v. 4, p. 30-34, 2014.
LEOPOLDINO, AM; Squarize, Cristiane H. ; Garcia, C.B. ; ALMEIDA, L. O. ; PESTANA, C. R. ; Uyemura, S.A. ; Tajara, EH ; GUTKIND, S. ; CURTI, C. . Accumulation of the SET protein in HEK293T cells and mild oxidative stress: cell survival or death signaling. Molecular and Cellular Biochemistry, v. 363, p. 65-74, 2012.
ALMEIDA, L. O. ; GOTO, R. N. ; PESTANA, C. R. ; Uyemura, S.A. ; GUTKIND, S. ; CURTI, C. ; Leopoldino AM . SET overexpression decreases cell detoxification efficiency: ALDH2 and GSTP1 are downregulated, DDR is impaired and DNA damage accumulates. The FEBS Journal (Print), v. 279, p. 4615-4628, 2012.
CARREGARO, F. ; CARTA, A. ; LOBO, S. A. ; Tajara, EH ; LEOPOLDINO, AM . Polymorphisms IL10-819 and TLR-2 are potentially associated with sepsis in Brazilian patients. Memórias do Instituto Oswaldo Cruz (Impresso), v. 105, p. 649-656, 2010.
LEOPOLDINO, AM; CANDURI, F ; CABRAL, H ; JUNQUEIRA, M ; DEMARQUI, A ; APPONI, L ; FONSECA, I ; DOMONT, G ; SANTOS, D ; VALENTINI, S . Expression, purification, and circular dichroism analysis of human CDK9. Protein Expression and Purification, Netherlands, v. 47, p. 614-620, 2006.
Bavoux C ; LEOPOLDINO, AM ; Ogi T ; Bieth A ; Kumari A ; Lehmann A ; PENA, S. D. J. ; Renato Machado C ; Hoffmann JS ; Cazaux C . Misregulation of the error-prone DNA polymerase kappa promotes pleiotropic genetic disorders and tumorigenesis. Cancer Research, v. 65, n.1, p. 325-330, 2005.
Anacleto, Charles ; Leopoldino, Andréia M. ; Rossi, Benedito ; Soares, Fernando A. ; Lopes, Ademar ; Rocha, José Cláudio C. ; Caballero, Otávia ; Camargo, Anamaria A. ; Simpson, Andrew J. G. ; Pena, Sérgio D. J. Colorectal Cancer “Methylator Phenotype”: Fact or Artifact?. Neoplasia (New York), v. 7, n.4, p. 331-335, 2005.
LEOPOLDINO, AM; PENA, S. D. J. . The mutational spectrum of human autosomal tetranucleotide microsatellites. Human Mutation, EUA, v. 21, n.1, p. 71-79, 2003.
LEOPOLDINO, AM; CARVALHOI, M. R. S. ; AGUIAR, M. J. B. ; PENA, S. D. J. . Prevalence of Prader-Willi and Angelman syndromes among mentally retarded boys in Brazil. Journal of Medical Genetics, EUA, v. 36, p. 498-498, 1999.
