Dr. Rodrigo Nalio Ramos

Cargo: Pesquisador Associado HC-FMUSP

Laboratório:

Telefone: 55 (11) 4573 7582

Lattes: http://lattes.cnpq.br/8126000030645922

Possui graduação em Ciências Biológicas pela Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP), Mestrado em Imunologia pela Universidade de São Paulo (USP) e dupla titulação de doutorado em Imunologia pela Universidade de São Paulo e pela Université de Lyon 1 (França). Foi pesquisador pós-doutorando do Centro de Imunoterapia do Câncer no Instituto Curie, Paris/França e pesquisador pós-doutorando do Centre de Recherche des Cordeliers/Sorbonne Université em Paris/França. Atualmente é pesquisador associado e orientador do programa de pós-graduação do Departamento de Ciências Médicas do HC-FMUSP e do Instituto D’OR de Ensino e Pesquisa em São Paulo. Tem experiência em projetos de pesquisa básica e translacional em onco-imunologia, com ênfase na caracterização de células mielóides e na resposta T contra tumores.

Linha de pesquisa:

Identification of specific T cell responses to tumor Neoepitopes in invaded Tumor-draining Lymph nodes;
High dimensional analysis of the myeloid cell landscape in human breast cancer metastatic lymph nodes.

Publicações:

1. NADER, GUILHERME PEDREIRA DE FREITAS ; AGÜERA-GONZALEZ, SONIA ; ROUTET, FIONA ; GRATIA, MATTHIEU ; MAURIN, MATHIEU ; CANCILA, VALERIA ; CADART, CLOTILDE ; PALAMIDESSI, ANDREA ; Ramos, Rodrigo Nalio ; SAN ROMAN, MABEL ; GENTILI, MATTEO ; YAMADA, AYAKO ; WILLIART, ALICE ; LODILLINSKY, CATALINA ; LAGOUTTE, EMILIE ; VILLARD, CATHERINE ; VIOVY, JEAN-LOUIS ; TRIPODO, CLAUDIO ; GALON, JÉRÔME ; SCITA, GIORGIO ; MANEL, NICOLAS ; CHAVRIER, PHILIPPE ; PIEL, MATTHIEU . Compromised nuclear envelope integrity drives TREX1-dependent DNA damage and tumor cell invasion. CELL, v. 184, p. 1-17, 2021.

2. PICANÇO-CASTRO, VIRGINIA ; BONAMINO, MARTÍN HERNAN ; Ramos, Rodrigo Nalio ; GUERINO-CUNHA, RENATO L. ; OLIVEIRA, THEO GREMEN M. ; REGO, EDUARDO M. . Associação Brasileira de Hematologia, Hemoterapia e Terapia Celular Consensus on genetically modified cells. VIII: CAR-T cells: preclinical development – Safety and efficacy evaluation. Hematology Transfusion And Cell Therapy, v. 43, p. S54-S63, 2021.

3. Ramos, Rodrigo Nalio; PICANÇO-CASTRO, VIRGINIA ; OLIVEIRA, THEO GREMEN M. ; MENDRONE, ALFREDO ; DE SANTIS, GIL CUNHA ; BONAMINO, MARTIN HERNAN ; ROCHA, VANDERSON . Associação Brasileira de Hematologia, Hemoterapia e Terapia Celular Consensus on genetically modified cells. VII. Present and future of technologies for production of CAR cell therapies. Hematology Transfusion And Cell Therapy, v. 43, p. S46-S53, 2021.

4. Ramos, Rodrigo Nalio; RODRIGUEZ, CÉLINE ; HUBERT, MARGAUX ; ARDIN, MAUDE ; TREILLEUX, ISABELLE ; RIES, CAROLA H ; LAVERGNE, EMILIE ; CHABAUD, SYLVIE ; COLOMBE, AMÉLIE ; TRÉDAN, OLIVIER ; GUEDES, HENRIQUE GOMES ; LAGINHA, FÁBIO ; RICHER, WILFRID ; Piaggio, Eliane ; BARBUTO, JOSÉ ALEXANDRE M ; CAUX, CHRISTOPHE ; MÉNÉTRIER’CAUX, CHRISTINE ; BENDRISS’VERMARE, NATHALIE . CD163 tumor-associated macrophage accumulation in breast cancer patients reflects both local differentiation signals and systemic skewing of monocytes. Clinical & Translational Immunology, v. 9, p. e1108, 2020.

Citações:

5. BOURDELY, PIERRE ; ANSELMI, GIORGIO ; VAIVODE, KRISTINE ; Ramos, Rodrigo Nalio ; MISSOLO-KOUSSOU, YOANN ; HIDALGO, SOFIA ; TOSSELO, JIMENA ; NUÑEZ, NICOLAS ; RICHER, WILFRID ; VINCENT-SALOMON, ANNE ; SAXENA, ALKA ; WOOD, KRISTIE ; LLADSER, ALVARO ; Piaggio, Eliane ; HELFT, JULIE ; GUERMONPREZ, PIERRE . Transcriptional and Functional Analysis of CD1c+ Human Dendritic Cells Identifies a CD163+ Subset Priming CD8+CD103+ T Cells. IMMUNITY, v. 53, p. 1, 2020.

Citações:

6. NÚÑEZ, NICOLAS GONZALO ; TOSELLO BOARI, JIMENA ; Ramos, Rodrigo Nalio ; RICHER, WILFRID ; CAGNARD, NICOLAS ; ANDERFUHREN, CYRILL DIMITRI ; NIBORSKI, LETICIA LAURA ; BIGOT, JEREMY ; MESEURE, DIDIER ; DE LA ROCHERE, PHILIPPE ; MILDER, MAUD ; VIEL, SOPHIE ; LOIRAT, DELPHINE ; PÉROL, LOUIS ; VINCENT-SALOMON, ANNE ; SASTRE-GARAU, XAVIER ; BURKHARD, BECHER ; SEDLIK, CHRISTINE ; LANTZ, OLIVIER ; AMIGORENA, SEBASTIAN ; Piaggio, Eliane . Tumor invasion in draining lymph nodes is associated with Treg accumulation in breast cancer patients. Nature Communications, v. 11, p. 3272, 2020.

Citações:

7. BURLION, AUDE ; RAMOS, RODRIGO N. ; KC, PUKAR ; SENDEYO, KÉLHIA ; CORNEAU, AURÉLIEN ; MÉNÉTRIER-CAUX, CHRISTINE ; Piaggio, Eliane ; OLIVE, DANIEL ; CAUX, CHRISTOPHE ; MARODON, GILLES . A novel combination of chemotherapy and immunotherapy controls tumor growth in mice with a human immune system. OncoImmunology, v. 8, p. e1596005, 2019.

Citações:

8. CABRAL-MARQUES, OTAVIO ; SCHIMKE, LENA F. ; DE OLIVEIRA, EDGAR BORGES ; EL KHAWANKY, NADIA ; Ramos, Rodrigo Nalio ; AL-RAMADI, BASEL K. ; SEGUNDO, GESMAR RODRIGUES SILVA ; Ochs, Hans D. ; . Flow Cytometry Contributions for the Diagnosis and Immunopathological Characterization of Primary Immunodeficiency Diseases With Immune Dysregulation. Frontiers in Immunology, v. 10, p. 2742, 2019.

Citações:

9. LERUSTE, AMAURY TOSELLO, JIMENA Ramos, Rodrigo Nalio TAUZIÈDE-ESPARIAT, ARNAULT BROHARD, SOLÈNE HAN, ZHI-YAN BECCARIA, KEVIN ANDRIANTERANAGNA, MAMY CAUDANA, PAMELA NIKOLIC, JOVAN CHAUVIN, CÉLINE NIBORSKI, LETICIA LAURA MANRIQUEZ, VALERIA RICHER, WILFRID MASLIAH-PLANCHON, JULIEN GROSSETÊTE-LALAMI, SANDRINE BOHEC, MYLENE LAMEIRAS, SONIA BAULANDE, SYLVAIN POUPONNOT, CELIO COULOMB, AURORE GALMICHE, LOUISE SURDEZ, DIDIER SERVANT, NICOLAS HELFT, JULIE , ; Clonally Expanded T Cells Reveal Immunogenicity of Rhabdoid Tumors. CANCER CELL, v. 36, p. 597-612.e8, 2019.

Citações:

10. TEIXEIRA, SARAH FERNANDES ; RODRIGUES, CECILIA PESSOA ; COSTA, CICERO JULIO SILVA ; PETTINATI, THAIS NARIMATSU ; DE AZEVEDO, RICARDO ALEXANDRE ; MAMBELLI, LISLEY INATA ; JORGE, SALOMAO DORIA ; Ramos, Rodrigo Nalio ; FERRO, EMER SUAVINHO ; Barbuto, Jose Alexandre Marzagão ; FERREIRA, ADILSON KLEBER . Edelfosine: an antitumor drug prototype. Anti-Cancer Agents in Medicinal Chemistry, v. 18, p. 865-874, 2018.

Citações: