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Publications

2021

MIRANDA, M. A.; MARCATO, P. D.; MONDAL, A.; CHOWDHURY, N.; GEBEYEHU, A.; SURAPANENI, S. K.; BENTLEY, M. V. L. B.; AMARAL, R.; PAN, C.-X.; SINGH, M. Cytotoxic and chemosensitizing effects of glycoalkaloidic extract on 2D and 3D models using RT4 and patient derived xenografts bladder cancer cells. Materials Science & Engineering C-Materials for Biological Applications v. 119, p. 111460, 2021.

LEITE, M. N.; VIEGAS, J. S. R.; PRAÇA, F.G.; PAULA, N. A.; BENTLEY, M.V. L. B.; FRADE, M. A. C.. Ex vivo model of human skin (hOSEC) for assessing the dermatokinetics of the anti-melanoma drug Dacarbazine. European Journal of Pharmaceutical Sciences, v. 160, p. 105769, 2021.

SUZUKI, I. L.; ARAUJO, M. M. de; BAGNATO, V. S.; BENTLEY, M. V. L. B. TNFα siRNA delivery by nanoparticles and photochemical internalization for psoriasis topical therapy. Journal of Controlled Release, v. 338, p. 316-329, 2021.

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2020

PRAÇA, F. G.; VIEGAS, J. S. R.; PEH, H. Y.; GARBIN, T. N.; MEDINA, W. S. G.; BENTLEY, M. V. L. B. Microemulsion co-delivering vitamin A and vitamin E as a new platform for topical treatment of acute skin inflammation. Materials Science & Engineering C-Materials for Biological Applications, v. 110, p. 110639, 2020.

DHARMASASAI; MANDAL, A.; QI, Q. M.; SUZUKI, I.; BENTLEY, M. V. L. B.; MITRAGOTRI, S. Topical Delivery of siRNA into Skin using Ionic Liquids. Journal of Controlled Release, v. 323, p. 475-482, 2020.

BORGHETI-CARDOSO, L. N.; VIEGAS, J. S. R.; SILVESTRINI, A. V. P.; CARON, A. L.; PRAÇA, F. G.; KRAVICZ, M.; BENTLEY, M. V. L. B. Nanotechnology approaches in the current therapy of skin cancer. Advanced Drug Delivery Reviews, v. 153, p. 109-136, 2020.

VIEGAS, J. S. R.; PRAÇA, F. G.; CARON, A. L.; SUZUKI, I.; SILVESTRINI, A. V. P.; MEDINA, W. S. G.; DEL CIAMPO, J. O.; KRAVICZ, M.; BENTLEY, M. V. L. B.. Nanostructured lipid carrier co-delivering tacrolimus and TNF-α siRNA as an innovate approach to psoriasis. Drug Delivery and Translational Research, v. 10, p. 646-660, 2020.

MIRANDA, M. A.; SILVA, L. B.; CARVALHO, I. P. S.; AMARAL, R.; DE PAULA, M. H.; SWIECH, K.; BASTOS, J. K.; PASCHOAL, J. A. R.; EMERY, F. S.; REIS, R. B. dos; BENTLEY, M. V. L. B.; MARCATO, P. D. Targeted uptake of folic acid-functionalized polymeric nanoparticles loading glycoalkaloidic extract in vitro and in vivo assays. Colloids and Surfaces B-Biointerfaces, v. 192, p. 111106, 2020.

CAMPOS, P. M.; PRAÇA, F. G.; MUSSI, S.V; FIGUEIREDO, S. A.; FANTINI, M. C. de A.; FONSECA, M. J. V.; TORCHILIN, V. P.; BENTLEY, MARIA V. L. B. Liquid crystalline nanodispersions functionalized with cell penetrating peptides improve skin penetration and the anti-inflammatory effects of lipoic acid after in vivo skin exposure to UVB radiation. Drug Delivery and Translational Research, v. 10, p. 1810-1828, 2020.

VIEGAS, J. S. R.; PRAÇA, F. G.; KRAVICZ, M.; BENTLEY, M. V. L. B. Therapeutic applications and delivery systems for triptolide. Drug Delivery and Translational Research, v. 10, p. 1584-1600, 2020.

SILVESTRINI, A. V. P.; CARON, A. L.; VIEGAS, J.; PRAÇA, F. G.; BENTLEY, M. V. L. B. Advances in lyotropic liquid crystal systems for skin drug delivery. Expert Opinion on Drug Delivery, v. 17, p. 1781-1805, 2020.

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2019

MIRANDA, M. A.; MARCATO, P. D.; CARVALHO, I. P. S.; SILVA, L. B.; RIBEIRO, D. L.; AMARAL, R.; SWIECH, K.; BASTOS, J. K.; PASCHOAL, J. A. R.; REIS, R. B. ; BENTLEY, M. V. L. B. Assessing the cytotoxic potential of glycoalkaloidic extract in nanoparticles against bladder cancer cells. JOURNAL OF PHARMACY AND PHARMACOLOGY , v. 71, p. 1520-1531, 2019.

KRAVICZ, M. H.; BALOGH, D. T.; KAR, M.; WEDEPOHL, S.; BENTLEY, M. V. L. B.; CALDERÓN, M. Influence of Alkyl Chains of Modified Polysuccinimide-Based Polycationic Polymers on Polyplex Formation and Transfection. MACROMOLECULAR BIOSCIENCE , v. 19, p. 1900117, 2019.

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2018

PRAÇA, F. S. G.; MEDINA, W. S. G.; ELOY, J. O.; PETRILLI, R.; CAMPOS, P. M.; ASCENSO, A.; BENTLEY, M. V. L. B. Evaluation of critical parameters for in vitro skin permeation and penetration studies using animal skin models. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES , v. 111, p. 121-132, 2018.

TOFANI, L. B.; DEPIERI, L. V.; CAMPOS, P. M.; Riul, T. B.; SWIECH, K.; FANTINI, M. C.; BENTLEY, M.V. B. In Vitro TyRP-1 Knockdown Based on siRNA Carried by Liquid Crystalline Nanodispersions: an Alternative Approach for Topical Treatment of Vitiligo. PHARMACEUTICAL RESEARCH , v. 35, p. 104-117, 2018.

ROSA, J.; SUZUKI, I.; KRAVICZ, M.; CARON, A.; PUPO, A. V.; PRACA, F. G.; BENTLEY, MARIA V. L. B. Current non-viral siRNA delivery systems as a promising treatment of skin diseases. CURRENT PHARMACEUTICAL DESIGN, v. 24, p. 2644-2663, 2018.

PRAÇA, F. G.; BENTLEY, M.V. L. B. Advances in Specific Gene Knockdown of Therapeutic Targets by RNA Interference. CURRENT PHARMACEUTICAL DESIGN, v. 24, p. 2631-2631, 2018.

AZARITE S., M. J. ; PRAÇA, F. G.; PEH, H. Y.; FOLONI, A. R.; SILVA, D. A. da; CARVALHO, B. M. de; BENTLEY, M. V. L. B.; MEDINA, W. S. G. Preparation and physicochemical characterization of Glyceryl monoolein bearing Cubosomes to improve Vitamin E delivery into the skin: A proposal for skin cancer prevention. Drug Delivery Letters, v. 08, p. 234-241, 2018.

ALMEIDA, E. D. P. ; D., L. V. ; ROSSETTI, F. C.; MARCHETTI, J. M.; BENTLEY, M. V. L. B.; NUNES, R. S.; SARMENTO, V. H. V.; VALERIO, M. E. G; JÚNIOR, J. J. R.; MONTALVÃO, M. M.; CORREA, C. B.; LIRA, A. A. M.. Skin permeation, biocompatibility and antitumor effect of chloroaluminum phthalocyanine associated to oleic acid in lipid nanoparticles. Photodiagnosis and Photodynamic Therapy, v. 24, p. 262-273, 2018.

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2017

ALIBERTI, A. L. M.; QUEIROZ, A. C. DE; PRAÇA, F. S. G.; ELOY, J. O.; BENTLEY, M. V. L. B.; MEDINA, W. S. G. Ketoprofen Microemulsion for Improved Skin Delivery and In Vivo Anti-inflammatory Effect. AAPS PharmSciTech , v. 1, p. 1-9, 2017.

BORGHETI-CARDOSO, L. N.; KOOIJMANS, S. A. A.; FENS, M. H. A. M.; DER MEEL, R. van; VICENTINI, F. T. M. de C.; FANTINI, M. C. de A.; BENTLEY, M. V. L. B. ; SCHIFFELERS, R. M. In Situ Gelling Liquid Crystalline System as Local siRNA Delivery System. MOLECULAR PHARMACEUTICS , v. 14, p. 1681-1690, 2017.

GARCIA, F. S.; PETRILLI, R.; ELOY, J. O.; LEE, R. J.; BENTLEY, M. V. L. B. Liquid-Crystalline Nanodispersions Containing Monoolein for Photodynamic Therapy of Skin Diseases: A Mini-Review. Current Nanoscience , v. 13, p. 528-535, 2017.

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2016

ROSSETTI, F. C.; DEPIERI, L. V.; PRAÇA, F. G.; Ciampo, José Orestes Del; FANTINI, M. C. de A.; PIERRE, M. B. R.; TEDESCO, A. C.; BENTLEY, M. V. L. B.. Optimization of protoporphyrin IX skin delivery for topical photodynamic therapy: Nanodispersions of liquid-crystalline phase as nanocarriers. European Journal of Pharmaceutical Sciences , v. 83, p. 99-108, 2016.

PETRILLI, R.; ELOY, J. O.; GARCIA, F. S.; CIAMPO, J. O. del; FANTINI, M. C.; FONSECA, M. J. V.; BENTLEY, M. V .L. B. Liquid Crystalline Nanodispersions Functionalized with Cell-Penetrating Peptides for Topical Delivery of Short-Interfering RNAs: A Proposal for Silencing a Pro-Inflammatory Cytokine in Cutaneous Diseases. Journal of Biomedical Nanotechnology , v. 12, p. 1063-1075, 2016.

DEPIERI, L. V. ; BORGHETI, L. N.; CAMPOS, P. M.; OTAGUIRI, K. K.; VICENTINI, F. T. M. de C.; Lopes, Luciana B. ; FONSECA, M. J. V. ; BENTLEY, M. V. L. B. RNAi mediated IL-6 in vitro knockdown in psoriasis skin model with topical siRNA delivery system based on liquid crystalline phase. European Journal of Pharmaceutics and Biopharmaceutics , v. 105, p. 50-58, 2016.

BORGHETI, L. N.; DEPIERI, L. M.; VICENTINI, F. T. M. de C.; BENTLEY, M. V. L. B. Terapia de interferência por RNA. Ciência Hoje, v. 56, p. 40-43, 2016.

LEZAMA-DÁVILA, C. M.; MCCHESNEY, J. D.; Bastos, J. K.; MIRANDA, M. A.; TIOSSI, R. F.; DA COSTA, J. DE C.; BENTLEY, M. V.; GAITAN-PUCH, S. E.; ISAAC-MÁRQUEZ, A. P. A New Antileishmanial Preparation of Combined Solamargine and Solasonine Heals Cutaneous Leishmaniasis through Different Immunochemical Pathways. Antimicrobial Agents and Chemotherapy (Print) , v. 60, p. 2732-2738, 2016.

BORGHETI-CARDOSO, L. N.; VICENTINI, F. T. M. de C.; GRATIERI, T. ; BENTLEY, M. V. L. B. Liquid crystalline systems containing Vitamin E TPGS for the controlled transdermal nicotine delivery. Brazilian Journal of Pharmaceutical Sciences (Online) , v. 52, p. 191-200, 2016.

MENEZES, A. C.; CAMPOS, P. M.; EULETÉRIO, C.; SIMÕES, S.; PRAÇA, F. S. G.; BENTLEY, M. V. L. B.; ASCENSO, A. Development and characterization of novel 1-(1-Naphthyl)piperazine-loaded lipid vesicles for prevention of UV-induced skin inflammation. European Journal of Pharmaceutics and Biopharmaceutics , v. 104, p. 101-109, 2016.

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2015

BORGHETI-CARDOSO, L. N. ; DEPIERI, L. V.; KOOIJMANS, S. A. A.; DINIZ, H.; CALZZANI, R. A. J.; VICENTINI, F. T. M. de C.; DER MEEL, R. van; FANTINI, M. C. de A.; IYOMASA, M. M.; SCHIFFELERS, R. M.; BENTLEY, M. V. L. B. An in situ gelling liquid crystalline system based on monoglycerides and polyethylenimine for local delivery of siRNAs. European Journal of Pharmaceutical Sciences , v. 74, p. 103-117, 2015.

DEPIERI, L. V.; PRAÇA, F. S. G.; CAMPOS, P. M.; BENTLEY, M. V. L. B. Advances in the bioanalytical study of drug delivery across the skin. Therapeutic Delivery, v. 6, p. 173-196, 2015.

CAMPOS, P. M.; PRAÇA, F. S. G.; BENTLEY, M. V. L. B. Quantification of lipoic acid from skin samples by HPLC using ultraviolet, electrochemical and evaporative light scattering detectors. Journal of Chromatography. B (Print) , v. 1, p. 1-20, 2015.

LOPES, L. B.; J GARCIA, M. T.; BENTLEY, M. V. L. B. Chemical penetration enhancers. Therapeutic Delivery, v. 6, p. 1053-1061, 2015.

ASCENSO, A.; BATISTA, C.; CARDOSO, P.; MENDES, T.; PRAÇA, F.; BENTLEY, V.; RAPOSO, S.; SIMÕES, S. Development, characterization, and skin delivery studies of related ultradeformable vesicles: transfersomes, ethosomes, and transethosomes. International Journal of Nanomedicine (Online) , v. 10, p. 5837-5851, 2015.

FREITAS, J. V.; PRAÇA, F. S. G.; BENTLEY, M. V. L. B.; GASPAR, L. R. Trans-resveratrol and beta-carotene from sunscreens penetrate viable skin layers and reduce cutaneous penetration of UV-filters. International Journal of Pharmaceutics (Print) , v. 484, p. 131-137, 2015.

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2014

TIOSSI, R. F. J. ; COSTA, J. C. ; Miranda, M. A.; GARCIA, F. S. Mcchesney, J. D.; BENTLEY, M. V. L. B.; BASTOS, J. K. In vitro and in vivo evaluation of the delivery of topical formulations containing glycoalkaloids of Solanum lycocarpum fruits. European Journal of Pharmaceutics and Biopharmaceutics , v. 88, p. 28-33, 2014.

BORGHETI, L. N. ; DEPIERI, L. V.; DINIZ, H.; CALZZANI, R. A. J.; FANTINI, M. C ; IYOMASA, M. M. ; VICENTINI, F. T. M. de C. ; BENTLEY, M. V. L. B. . Self-assembling gelling formulation based on a crystalline-phase liquid as a non-viral vector for siRNA delivery. European Journal of Pharmaceutical Sciences , v. 58, p. 72-82, 2014.

ASCENSO, A.; SALGADO, A.; EULETÉRIO, C.; PRAÇA, F. G.; BENTLEY, M. V. L. B.; MARQUES, H. C.; OLIVEIRA, H.; SANTOS, C.; SIMÕES, S. In vitro and in vivo topical delivery studies of tretinoin-loaded ultradeformable vesicles. European Journal of Pharmaceutics and Biopharmaceutics , v. 88, p. 48-55, 2014.

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2013

FINKLER, C. L.; SANTANA, M. H. A.; BENTLEY, M. V. L. B. Physicochemical characterization of surfactant incorporating vesicles that incorporate colloidal magnetite. Journal of Liposome Research , v. 23, p. 47-53, 2013.

VICENTINI, F. T. M. DE C.; BORGHETI-CARDOSO, L. N.; DEPIERI, L. V.; MANO, D. M.; ABELHA, T. F.; PETRILLI, R.; BENTLEY, M. V. L. B. Delivery Systems and Local Administration Routes for Therapeutic siRNA. Pharmaceutical Research , v. 30, p. 915-931, 2013.

PETRILLI, R.; CAROLLO, A. R. H.; OLIVEIRA, K. T.; FANTINI, M. C.; NEVES, M. G. P. M. S.; CAVALEIRO, J. A. S.; SERRA, O.; IAMAMOTO, Y.; BENTLEY, M. V. L. B. Nanoparticles of Lyotropic Liquid Crystals: A Novel Strategy for the Topical Delivery of a Chlorin Derivative for Photodynamic Therapy of Skin Cancer. Current Nanoscience , v. 9, p. 434-441, 2013.

SILVA, C. L. ; Ciampo, J. O. del; Rossetti, F. C.; Bentley, M. V. L. B.; PIERRE, M. B. R. PLGA Nanoparticles as Delivery Systems for Protoporphyrin IX in Topical PDT: Cutaneous Penetration of Photosensitizer Observed by Fluorescence Microscopy. Journal of Nanoscience and Nanotechnology (Print) , v. 13, p. 6533-6540, 2013.

VICENTINI, F. T. M. de C.; DEPIERI, L. V.; POLIZELLO, A. C. M.; Ciampo, José Orestes del; SPADARO, A. C. C.; FANTINI, M. C. A.; BENTLEY, M. V. L. B. Liquid crystalline phase nanodispersions enable skin delivery of siRNA. European Journal of Pharmaceutics and Biopharmaceutics , v. 83, p. 16-24, 2013.

ASCENSO, A.; PINHO, S.; ELEUTÉRIO, C.; PRAÇA, F. G.; BENTLEY, Maria V. L. B.; OLIVEIRA, H.; SANTOS, C.; SILVA, O.; SIMÕES, S. Lycopene from Tomatoes: Vesicular Nanocarrier Formulations for Dermal Delivery. Journal of Agricultural and Food Chemistry , v. 61, p. 7284-7293, 2013.

DA SILVA, C. L. ; CIAMPO, J. O. del; ROSSETTI, F. C. ; BENTLEY, M. V. L. B.; PIERRE, M. B. R. Improved In vitro and In vivo Cutaneous Delivery of Protoporphyrin IX from PLGA-based Nanoparticles. Photochemistry and Photobiology, v. 89, p. n/a-n/a, 2013.

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2012

ISSA, J. P. M.; DEFINO, H. L. A.; PEREIRA, Y. C. L.; NETTO, J. C.; SEBALD, W.; BENTLEY, M. V. L. B.; IYOMASA, M. M.; ERVOLINO, E. Bone repair investigation using rhBMP-2 and angiogenic protein extracted from latex. Microscopy Research and Technique (Print) , v. 75, p. 145-152, 2012.

TIOSSI, R. F. J.; MIRANDA, M. A.; Sousa, J. P. B. de; PRAÇA, F. S. G.; BENTLEY, M. V. L. B.; MCCHESNEY, J. D.; BASTOS, J. K. A Validated Reverse Phase HPLC Analytical Method for Quantitation of Glycoalkaloids in Solanum lycocarpum and Its Extracts. Journal of Analytical Methods in Chemistry , v. 2012, p. 1-8, 2012.

PRAÇA, F. S. G.; GARCIA, W. S.; PETRILLI, R.; BENTLEY, M. V. L. B. Liquid Crystal Nanodispersions Enable the Cutaneous Delivery of Photosensitizer for Topical PDT: Fluorescence Microscopy Study of Skin Penetration. Current Nanoscience, v. 8, p. 535-540, 2012.

MINARINI, P. R. R.; SOUZA, A. O. de; SOARES, E. G.; BARATA, L. E. S.; SILVA, C. L.; BENTLEY, M. V. L. B. Antimycobacterial activity of 2-phenoxy-1-phenylethanone, a synthetic analogue of neolignan, entrapped in polymeric microparticles. Drug Development and Industrial Pharmacy (Print) , v. 38, p. 259-263, 2012.

TIOSSI, R. J.; COSTA, J. C.; MIRANDA, M. A.; GARCIA, F. S.; MCCHESNEY, J. D.; BENTLEY, M. V. L. B.; BASTOS, J. K. A validated HPLC analytical method for the analysis of solasonine and solamargine in in vitro skin penetration studies. Química Nova (Impresso) , v. 35, p. 2312-2316, 2012.

ISSA, J. P. M.; DEFINO, H. L. A.; SEBALD, W.; COUTINHO-NETTO, J.; IYOMASA, M. M.; SHIMANO, A. C.; BENTLEY, M. V. L. B.; PITOL, D. L. Biological evaluation of the bone healing process after application of two potentially osteogenic proteins: an animal experimental model. Gerodontology , v. 29, p. 258-264, 2012.

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2011

VICENTINI, F. T. M. C. ; VAZ, M. M. O. L. L.; FONSECA, Y. M.; BENTLEY, M. V. L. B.; FONSECA, M. J. V. Characterization and stability study of a water-in-oil microemulsion incorporating quercetin. Drug Development and Industrial Pharmacy (Print) , v. 37, p. 47-55, 2011.

ROSSETTI, Fábia Cristina ; Fantini, Márcia C. A. ; Carollo, Aline Regina H. ; TEDESCO, Antônio Cláudio ; Lopes Badra Bentley, Maria Vitória ; BENTLEY, Maria Vitória Lopes Badra . Analysis of liquid crystalline nanoparticles by small angle X-ray diffraction: Evaluation of drug and pharmaceutical additives influence on the internal structure. Journal of Pharmaceutical Sciences , v. 100, p. 2849-2857, 2011.