Otávio Cabral Marques

Cargo: Pesquisador colaborador

Laboratório:

Telefone: 55 (11) 3091 7397

Lattes: http://lattes.cnpq.br/9691042906384364

Otávio Cabral-Marques is a Scientist at the Department of Immunology/Institute of Biomedical Sciences and the Department of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, both at the University of São Paulo. Biologist (2001-2005), He obtained his MSc (2006-2008) and PhD (2008-2012) degrees from the Institute of Biomedical Sciences – University of São Paulo (USP), performing his Sandwich PhD (Dec, 2010 – May, 2011) at the University of Washington/Seattle Children’s Research Institute, USA. Otávio performed his Post-doctorate in Brazil (USP: 2012 – 2015) and Germany (University of Lubeck, Oct, 2015 – April, 2018; University of Freiburg: Apr, 2015 – Nov, 2019). Otavio is the Brazilian Junior Ambassador of the Universal Scientific Education and Research Network (USERN).

Research lines:

Análise sistêmica e integrativa dos mecanismos de exaustão dos linfócitos T de pacientes com COVID-19;
Análise sistêmica e integrativa da resposta imune às infecções virais por Zika e Dengue;
Immunological and gene signatures associated with villous atrophy in common variable immunodeficiency;
The role of muscarinic acetylcholine receptors in the neutrophil ontogeny.

Publications:

1. FREIRE, PAULA P. ; MARQUES, ALEXANDRE H.C. ; BAIOCCHI, GABRIELA C. ; SCHIMKE, LENA F. ; FONSECA, DENNYSON L.M. ; SALGADO, RANIERI C. ; FILGUEIRAS, IGOR S. ; NAPOLEAO, SARAH M.S. ; PLAÇA, DESIRÉE R. ; AKASHI, KAREN T. ; HIRATA, THIAGO DOMINGUEZ CRESPO ; EL KHAWANKY, NADIA ; GIIL, LASSE M. ; CABRAL-MIRANDA, GUSTAVO ; CARVALHO, ROBSON F. ; FERREIRA, LUIS CARLOS S. ; CONDINO-NETO, ANTONIO ; NAKAYA, HELDER I. ; JURISICA, IGOR ; OCHS, HANS D. ; CAMARA, NIELS OLSEN SARAIVA ; CALICH, VERA LÚCIA G. ; CABRAL-MARQUES, OTAVIO . The relationship between cytokine and neutrophil gene network distinguishes SARS-CoV-2-infected patients by sex and age. JCI INSIGHT, v. 6, p. 147535, 2021.

Citações:

2. FRANÇA, TÁBATA T. ; AL-SBIEI, ASHRAF ; BASHIR, GHADA ; MOHAMED, YASSIR A. ; SALGADO, RANIERI C. ; BARREIROS, LUCILA A. ; DA SILVA NAPOLEÃO, SARAH M. ; WEBER, CRISTINA W. ; FERREIRA, JANÁIRA F.S. ; ARANDA, CAROLINA S. ; Prando, Carolina ; DE BARROS DORNA, MAYRA B. ; JURISICA, IGOR ; FERNANDEZ-CABEZUDO, MARIA J. ; OCHS, HANS D. ; CONDINO-NETO, ANTONIO ; AL-RAMADI, BASEL K. ; CABRAL-MARQUES, OTAVIO . CD40 ligand modulates transcriptional signatures of neutrophils in the bone marrow associated with development and trafficking. JCI INSIGHT, v. 6, p. 14, 2021.

3. KHAN, ANWAR SHEED ; PHELAN, JODY E. ; KHAN, MUHAMMAD TAHIR ; ALI, SAJID ; QASIM, MUHAMMAD ; NAPIER, GARY ; CAMPINO, SUSANA ; AHMAD, SAJJAD ; CABRAL-MARQUES, OTAVIO ; ZHANG, SHULIN ; RAHMAN, HAZIR ; WEI, DONG-QING ; CLARK, TAANE G. ; KHAN, TAJ ALI . Characterization of rifampicin-resistant Mycobacterium tuberculosis in Khyber Pakhtunkhwa, Pakistan. Scientific Reports, v. 11, p. 14194, 2021.

Citações:

4. FILGUEIRAS, IGOR SALERNO ; TORRENTES DE CARVALHO, AMANDA ; CUNHA, DANIELA PRADO ; MATHIAS DA FONSECA, DENNYSON LEANDRO ; EL KHAWANKY, NADIA ; FREIRE, PAULA PACCIELLI ; CABRAL-MIRANDA, GUSTAVO ; SCHIMKE, LENA F. ; CAMARA, NIELS OLSEN SARAIVA ; OCHS, HANS D. ; PERON, JEAN PIERRE SCHATZMANN ; CABRAL-MARQUES, OTÁVIO ; DE VASCONCELOS, ZILTON FARIAS MEIRA . The clinical spectrum and immunopathological mechanisms underlying ZIKV-induced neurological manifestations. PLoS Neglected Tropical Diseases, v. 15, p. e0009575, 2021.

5. SALGADO, RANIERI COELHO ; FONSECA, DENNYSON LEANDRO M. ; MARQUES, ALEXANDRE H. C. ; DA SILVA NAPOLEAO, SARAH MARIA ; FRANÇA, TÁBATA TAKAHASHI ; AKASHI, KAREN TIEMI ; DE SOUZA PRADO, CAROLINE ALIANE ; BAIOCCHI, GABRIELA CRISPIM ; PLAÇA, DESIRÉE RODRIGUES ; JANSEN-MARQUES, GABRIEL ; FILGUEIRAS, IGOR SALERNO ; DE VITO, ROBERTA ; FREIRE, PAULA PACCIELLI ; DE MIRANDA, GUSTAVO CABRAL ; CAMARA, NIELS OLSEN SARAIVA ; CALICH, VERA LÚCIA GARCIA ; OCHS, HANS D. ; SCHIMKE, LENA F. ; JURISICA, IGOR ; CONDINO-NETO, ANTONIO ; CABRAL-MARQUES, OTAVIO . The network interplay of interferon and Toll-like receptor signaling pathways in the anti-Candida immune response. Scientific Reports, v. 11, p. 1, 2021.

6. KAPPES, LUCY AMER, RUBA L. SOMMERLATTE, SABINE BASHIR, GHADA PLATTFAUT, CORINNA GIESELER, FRANK GEMOLL, TIMO BUSCH, HAUKE ALTAHRAWI, ABEER AL-SBIEI, ASHRAF HANEEFA, SHOJA M. ARAFAT, KHOLOUD SCHIMKE, LENA F. KHAWANKY, NADIA EL SCHULZE-FORSTER, KAI HEIDECKE, HARALD KERSTEIN-STAEHLE, ANJA MARSCHNER, GABRIELE PITANN, SILKE OCHS, HANS D. MUELLER, ANTJE ATTOUB, SAMIR FERNANDEZ-CABEZUDO, MARIA J. RIEMEKASTEN, GABRIELA AL-RAMADI, BASEL K. , ; Ambrisentan, an endothelin receptor type A-selective antagonist, inhibits cancer cell migration, invasion, and metastasis. Scientific Reports, v. 10, p. 15931, 2020.

Citações:

7. ARYAPPALLI, PRIYANKA ; SHABBIRI, KHADIJA ; MASAD, RAZAN J. ; AL-MARRI, ROADHA H. ; HANEEFA, SHOJA M. ; MOHAMED, YASSIR A. ; ARAFAT, KHOLOUD ; ATTOUB, SAMIR ; CABRAL-MARQUES, OTAVIO ; RAMADI, KHALIL B. ; FERNANDEZ-CABEZUDO, MARIA J. ; AL-RAMADI, BASEL K. . Inhibition of Tyrosine-Phosphorylated STAT3 in Human Breast and Lung Cancer Cells by Manuka Honey is Mediated by Selective Antagonism of the IL-6 Receptor. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v. 20, p. 4340, 2019.

Citações:

8. UL AKBAR, NOOR ; KHAN, SHAHID NIAZ ; AMIN, MUHAMMAD USMAN ; ISHFAQ, MUHAMMAD ; CABRAL-MARQUES, OTAVIO ; SCHIMKE, LENA F ; IQBAL, ASIF ; ULLAH, IKRAM ; HUSSAIN, MUBASHIR ; ALI, IJAZ ; KHAN, NASAR ; EL KHAWANKY, NADIA ; RAHMAN, HAZIR ; KHAN, TAJ ALI . Novel nonsense IL-12Rβ1 mutation associated with recurrent tuberculosis. IMMUNOLOGIC RESEARCH, v. 67, p. 1, 2019.

9. CABRAL-MARQUES, OTAVIO; SCHIMKE, LENA F. ; DE OLIVEIRA, EDGAR BORGES ; EL KHAWANKY, NADIA ; RAMOS, RODRIGO NALIO ; AL-RAMADI, BASEL K. ; SEGUNDO, GESMAR RODRIGUES SILVA ; OCHS, HANS D. ; CONDINO-NETO, ANTONIO . Flow Cytometry Contributions for the Diagnosis and Immunopathological Characterization of Primary Immunodeficiency Diseases With Immune Dysregulation. Frontiers in Immunology, v. 10, p. 89, 2019.

Citações:

10. FRANÇA, TABATA T. ; BARREIROS, LUCILA A. ; AL-RAMADI, BASEL K. ; Ochs, Hans D. ; CABRAL-MARQUES, OTÁVIO ; CONDINO-NETO, A. . CD40 ligand deficiency: treatment strategies and novel therapeutic perspectives. Expert Review of Clinical Immunology, v. 15, p. 529-540, 2019.

Citações: