Publicações

2022

Lazari LC, Rosa-Fernandes L, Palmisano G. Machine Learning Approaches to Analyze MALDI-TOF Mass Spectrometry Protein Profiles. Methods Mol Biol. 2022;2511:375-394. doi: 10.1007/978-1-0716-2395-4_29. PMID: 35838976.

Lazari LC, Rosa-Fernandes L, Palmisano G. Identification of Circulating Biomarkers of COVID-19 Using MALDI-TOF Mass Spectrometry. Methods Mol Biol. 2022;2511:175-182. doi: 10.1007/978-1-0716-2395-4_13. PMID: 35838960.

Macedo-da-Silva J, Coutinho JVP, Rosa-Fernandes L, Marie SKN, Palmisano G. Exploring COVID-19 pathogenesis on command-line: A bioinformatics pipeline for handling and integrating omics data. Adv Protein Chem Struct Biol. 2022;131:311-339. doi: 10.1016/bs.apcsb.2022.04.002. Epub 2022 May 12. PMID: 35871895; PMCID: PMC9095070.

Rosa-Fernandes L, Bedrat A, Dos Santos MLB, Pinto AMV, Lucena E, Silva TP, Melo RCN, Palmisano G, Cardoso CA, Barbosa RH. Global RNAseq of ocular cells reveals gene dysregulation in both asymptomatic and with Congenital Zika Syndrome infants exposed prenatally to Zika virus. Exp Cell Res. 2022 May 15;414(2):113086. doi: 10.1016/j.yexcr.2022.113086. Epub 2022 Mar 10. PMID: 35283101.

Lazari LC, Zerbinati RM, Rosa-Fernandes L, Santiago VF, Rosa KF, Angeli CB, Schwab G, Palmieri M, Sarmento DJS, Marinho CRF, Almeida JD, To K, Giannecchini S, Wrenger C, Sabino EC, Martinho H, Lindoso JAL, Durigon EL, Braz-Silva PH, Palmisano G. MALDI-TOF mass spectrometry of saliva samples as a prognostic tool for COVID-19. J Oral Microbiol. 2022 Feb 27;14(1):2043651. doi: 10.1080/20002297.2022.2043651. PMID: 35251522; PMCID: PMC8890567.

Monteiro Júnior JC, Krüger A, Palmisano G, Wrenger C. Transporter-Mediated Solutes Uptake as Drug Target in Plasmodium falciparum. Front Pharmacol. 2022 Feb 7;13:845841. doi: 10.3389/fphar.2022.845841. PMID: 35370717; PMCID: PMC8965513.

Coutinho JVP, Macedo-da-Silva J, Mule SN, Kronenberger T, Rosa-Fernandes L, Wrenger C, Palmisano G. Glycoprotein molecular dynamics analysis: SARS-CoV-2 spike glycoprotein case study. Adv Protein Chem Struct Biol. 2022;131:277-309. doi: 10.1016/bs.apcsb.2022.05.004. Epub 2022 Jun 9. PMID: 35871894; PMCID: PMC9181370.

Kawahara R, Chernykh A, Alagesan K, Bern M, Cao W, Chalkley RJ, Cheng K, Choo MS, Edwards N, Goldman R, Hoffmann M, Hu Y, Huang Y, Kim JY, Kletter D, Liquet B, Liu M, Mechref Y, Meng B, Neelamegham S, Nguyen-Khuong T, Nilsson J, Pap A, Park GW, Parker BL, Pegg CL, Penninger JM, Phung TK, Pioch M, Rapp E, Sakalli E, Sanda M, Schulz BL, Scott NE, Sofronov G, Stadlmann J, Vakhrushev SY, Woo CM, Wu HY, Yang P, Ying W, Zhang H, Zhang Y, Zhao J, Zaia J, Haslam SM, Palmisano G, Yoo JS, Larson G, Khoo KH, Medzihradszky KF, Kolarich D, Packer NH, Thaysen-Andersen M. Author Correction: Community evaluation of glycoproteomics informatics solutions reveals high-performance search strategies for serum glycopeptide analysis. Nat Methods. 2022 Jan;19(1):130. doi: 10.1038/s41592-021-01368-0. Erratum for: Nat Methods. 2021 Nov;18(11):1304-1316. PMID: 34893784; PMCID: PMC8748192.

Carneiro A, Macedo-da-Silva J, Santiago VF, de Oliveira GS, Guimarães T, Mendonça CF, de Oliveira Branquinho JL, Lucena CV, Osório J, Pernambuco E, Moreira JC, Pesquero JB, Pereira MD, Palmisano G. Urine proteomics as a non-invasive approach to monitor exertional rhabdomyolysis during military training. J Proteomics. 2022 Apr 30;258:104498. doi: 10.1016/j.jprot.2022.104498. Epub 2022 Feb 5. PMID: 35134564.

2021

Kischkel B, Boniche-Alfaro C, Menezes IG, Rossi SA, Angeli CB, de Almeida SR, Palmisano G, Lopes-Bezerra L, Nosanchuk JD, Taborda CP. Immunoproteomic and Immunopeptidomic Analyses of Histoplasma capsulatum Reveal Promiscuous and Conserved Epitopes Among Fungi With Vaccine Potential. Front Immunol. 2021 Nov 22;12:764501. doi: 10.3389/fimmu.2021.764501. PMID: 34880863; PMCID: PMC8645968.

Souza Junior DR, Silva ARM, Rosa-Fernandes L, Reis LR, Alexandria G, Bhosale SD, Ghilardi FR, Dalçóquio TF, Bertolin AJ, Nicolau JC, Marinho CRF, Wrenger C, Larsen MR, Siciliano RF, Di Mascio P, Palmisano G, Ronsein GE. HDL proteome remodeling associates with COVID-19 severity. J Clin Lipidol. 2021 Nov-Dec;15(6):796-804. doi: 10.1016/j.jacl.2021.10.005. Epub 2021 Oct 31. PMID: 34802985; PMCID: PMC8557113.

Kawahara, R., Chernykh, A., Alagesan, K. et al. Community evaluation of glycoproteomics informatics solutions reveals high-performance search strategies for serum glycopeptide analysis. Nat Methods 18, 1304–1316 (2021). https://doi.org/10.1038/s41592-021-01309-x

Trombetta-Lima M, Rosa-Fernandes L, Angeli CB, Moretti IF, Franco YM, Mousessian AS, Wakamatsu A, Lerario AM, Oba-Shinjo SM, Pasqualucci CA, Marie SKN, Palmisano G. Extracellular Matrix Proteome Remodeling in Human Glioblastoma and Medulloblastoma. J Proteome Res. 2021 Oct 1;20(10):4693-4707. doi: 10.1021/acs.jproteome.1c00251. Epub 2021 Sep 17. PMID: 34533964.

Rosa-Fernandes L, Bandeira C, Pour SZ, Benedetti VF, Ferreira D, Lorenzon AR, Moreli JB, Marinho CRF, Larsen MR, Zanotto P, Palmisano G, Bevilacqua E. The impact of Zika virus exposure on the placental proteomic profile. Biochim Biophys Acta Mol Basis Dis. 2022 Jan 1;1868(1):166270. doi: 10.1016/j.bbadis.2021.166270. Epub 2021 Sep 25. PMID: 34582966.

Mule SN, Rosa-Fernandes L, Coutinho JVP, Gomes VM, Macedo-da-Silva J, Santiago VF, Quina D, de Oliveira GS, Thaysen-Andersen M, Larsen MR, Labriola L, Palmisano G. Systems-wide analysis of glycoprotein conformational changes by limited deglycosylation assay. J Proteomics. 2021 Sep 30;248:104355. doi: 10.1016/j.jprot.2021.104355. Epub 2021 Aug 24. PMID: 34450331.

Coutinho JVP, Rosa-Fernandes L, Mule SN, de Oliveira GS, Manchola NC, Santiago VF, Colli W, Wrenger C, Alves MJM, Palmisano G. The thermal proteome stability profile of Trypanosoma cruzi in epimastigote and trypomastigote life stages. J Proteomics. 2021 Sep 30;248:104339. doi: 10.1016/j.jprot.2021.104339. Epub 2021 Aug 2. PMID: 34352427.

Lazari LC, Ghilardi FR, Rosa-Fernandes L, Assis DM, Nicolau JC, Santiago VF, Dalçóquio TF, Angeli CB, Bertolin AJ, Marinho CR, Wrenger C, Durigon EL, Siciliano RF, Palmisano G. Prognostic accuracy of MALDI-TOF mass spectrometric analysis of plasma in COVID-19. Life Sci Alliance. 2021 Jun 24;4(8):e202000946. doi: 10.26508/lsa.202000946. PMID: 34168074; PMCID: PMC8321665.

Gomes LC, Sanson MCG, Brainin P, de Melo MDCV, de Souza RM, Mazaro J, Lima KO, Resende JS, Vieira IVM, Mesquita EDS, Matos LO, Dutra ICS, Palmisano G, Wrenger C, Marinho CRF, da Silva RDSU. Levels of hepatitis B antibody titers are affected by age and doses gap time in children from a high endemic area of the western Amazon. PLoS One. 2021 Jul 1;16(7):e0253752. doi: 10.1371/journal.pone.0253752. PMID: 34197516; PMCID: PMC8248698.

Macedo-da-Silva J, Santiago VF, Rosa-Fernandes L, Marinho CRF, Palmisano G. Protein glycosylation in extracellular vesicles: Structural characterization and biological functions. Mol Immunol. 2021 Jul;135:226-246. doi: 10.1016/j.molimm.2021.04.017. Epub 2021 Apr 29. PMID: 33933815.

SARS-CoV-2 activates ER stress and Unfolded protein response

Livia Rosa-Fernandes, Lucas C. Lazari, Janaina Macedo da Silva, Vinicius de Morais Gomes, Rafael Rahal Guaragna Machado, Ancely Ferreira dos Santos, Danielle Bastos Araujo, João Vitor Paccini Coutinho, Gabriel Santos Arini, Claudia B. Angeli, Edmarcia E. de Souza, Carsten Wrenger, Claudio R. F. Marinho, Danielle B. L. Oliveira, Edison L. Durigon, Leticia Labriola, Giuseppe Palmisano

bioRxiv 2021.06.21.449284; doi: https://doi.org/10.1101/2021.06.21.449284

Sumam de Oliveira D, Kronenberger T, Palmisano G, Wrenger C, de Souza EE. Targeting SUMOylation in Plasmodium as a Potential Target for Malaria Therapy. Front Cell Infect Microbiol. 2021 Jun 10;11:685866. doi: 10.3389/fcimb.2021.685866. PMID: 34178724; PMCID: PMC8224225.

Cavalcante T, Medeiros MM, Mule SN, Palmisano G, Stolf BS. The Role of Sialic Acids in the Establishment of Infections by Pathogens, With Special Focus on Leishmania. Front Cell Infect Microbiol. 2021 May 13;11:671913. doi: 10.3389/fcimb.2021.671913. PMID: 34055669; PMCID: PMC8155805.

Carneiro A, Viana-Gomes D, Macedo-da-Silva J, Lima GHO, Mitri S, Alves SR, Kolliari-Turner A, Zanoteli E, Neto FRA, Palmisano G, Pesquero JB, Moreira JC, Pereira MD. Risk factors and future directions for preventing and diagnosing exertional rhabdomyolysis. Neuromuscul Disord. 2021 Jul;31(7):583-595. doi: 10.1016/j.nmd.2021.04.007. Epub 2021 May 6. PMID: 34193371.

Mule SN, Gomes VM, Wailemann RAM, Macedo-da-Silva J, Rosa-Fernandes L, Larsen MR, Labriola L, Palmisano G. HSPB1 influences mitochondrial respiration in ER-stressed beta cells. Biochim Biophys Acta Proteins Proteom. 2021 Sep;1869(9):140680. doi: 10.1016/j.bbapap.2021.140680. Epub 2021 May 27. PMID: 34051341.

Dombrowski JG, Barateiro A, Peixoto EPM, Barros ABCDS, Souza RM, Clark TG, Campino S, Wrenger C, Wunderlich G, Palmisano G, Epiphanio S, Gonçalves LA, Marinho CRF. Adverse pregnancy outcomes are associated with Plasmodium vivax malaria in a prospective cohort of women from the Brazilian Amazon. PLoS Negl Trop Dis. 2021 Apr 29;15(4):e0009390. doi: 10.1371/journal.pntd.0009390. PMID: 33914739; PMCID: PMC8112668.

Kawahara R, Chernykh A, Alagesan K, Bern M, Cao W, Chalkley RJ, Cheng K, Choo MS, Edwards N, Goldman R, Hoffmann M, Hu Y, Huang Y, Kim JY, Kletter D, Liquet B, Liu M, Mechref Y, Meng B, Neelamegham S, Nguyen-Khuong T, Nilsson J, Pap A, Park GW, Parker BL, Pegg CL, Penninger JM, Phung TK, Pioch M, Rapp E, Sakalli E, Sanda M, Schulz BL, Scott NE, Sofronov G, Stadlmann J, Vakhrushev SY, Woo CM, Wu HY, Yang P, Ying W, Zhang H, Zhang Y, Zhao J, Zaia J, Haslam SM, Palmisano G, Yoo JS, Larson G, Khoo KH, Medzihradszky KF, Kolarich D, Packer NH, Thaysen-Andersen M. Community evaluation of glycoproteomics informatics solutions reveals high-performance search strategies for serum glycopeptide analysis. Nat Methods. 2021 Nov;18(11):1304-1316. doi: 10.1038/s41592-021-01309-x. Epub 2021 Nov 1. Erratum in: Nat Methods. 2021 Dec 10;: Erratum in: Nat Med. 2022 Jan;28(1):214. PMID: 34725484; PMCID: PMC8566223.

Mule SN, Costa-Martins AG, Rosa-Fernandes L, de Oliveira GS, Rodrigues CMF, Quina D, Rosein GE, Teixeira MMG, Palmisano G. PhyloQuant approach provides insights into Trypanosoma cruzi evolution using a systems-wide mass spectrometry-based quantitative protein profile. Commun Biol. 2021 Mar 11;4(1):324. doi: 10.1038/s42003-021-01762-6. PMID: 33707618; PMCID: PMC7952728.

Mule SN, Manchola NC, de Oliveira GS, Pereira M, Magalhães RDM, Teixeira AA, Colli W, Alves MJM, Palmisano G. Proteome-wide modulation of S-nitrosylation in Trypanosoma cruzi trypomastigotes upon interaction with the host extracellular matrix. J Proteomics. 2021 Jan 16;231:104020. doi: 10.1016/j.jprot.2020.104020. Epub 2020 Oct 20. PMID: 33096306.

Priscila R. dos Santos-Donado, Carlos M. Donado-Pestana, Rebeca Kawahara, Livia Rosa-Fernandes, Giuseppe Palmisano, Flavio Finardi-Filho,
Comparative analysis of the protein profile from biofortified cultivars of quality protein maize and conventional maize by gel-based and gel-free proteomic approaches,
LWT, https://doi.org/10.1016/j.lwt.2020.110683.

Kawahara R, Recuero S, Srougi M, Leite KRM, Thaysen-Andersen M, Palmisano G. The Complexity and Dynamics of the Tissue Glycoproteome Associated With Prostate Cancer Progression. Mol Cell Proteomics. 2021;20:100026. doi: 10.1074/mcp.RA120.002320. Epub 2021 Jan 5. PMID: 33127837; PMCID: PMC8010466.

Tsakaneli A, Carregari VC, Morini M, Eva A, Cangemi G, Chayka O, Makarov E, Bibbò S, Capone E, Sala G, De Laurenzi V, Poon E, Chesler L, Pieroni L, Larsen MR, Palmisano G, Sala A. MYC regulates metabolism through vesicular transfer of glycolytic kinases. Open Biol. 2021 Dec;11(12):210276. doi: 10.1098/rsob.210276. Epub 2021 Dec 1. PMID: 34847775; PMCID: PMC8633805.

2020

Martins LA, Palmisano G, Cortez M, Kawahara R, de Freitas Balanco JM, Fujita A, Alonso BI, Barros-Battesti DM, Braz GRC, Tirloni L, Esteves E, Daffre S, Fogaça AC. The intracellular bacterium Rickettsia rickettsii exerts an inhibitory effect on the apoptosis of tick cells. Parasit Vectors. 2020 Dec 1;13(1):603. doi: 10.1186/s13071-020-04477-5. PMID: 33261663; PMCID: PMC7706286.

Macedo-da-Silva J, Rosa-Fernandes L, Barbosa RH, Angeli CB, Carvalho FR, de Oliveira Vianna RA, Carvalho PC, Larsen MR, Cardoso CA, Palmisano G. Serum Proteomics Reveals Alterations in Protease Activity, Axon Guidance, and Visual Phototransduction Pathways in Infants With In Utero Exposure to Zika Virus Without Congenital Zika Syndrome. Front Cell Infect Microbiol. 2020 Nov 18;10:577819. doi: 10.3389/fcimb.2020.577819. PMID: 33312964; PMCID: PMC7708324.

Rodrigues MAD, Pimenta MV, Costa IM, Zenatti PP, Migita NA, Yunes JA, Rangel-Yagui CO, de Sá MM, Pessoa A, Costa-Silva TA, Toyama MH, Breyer CA, de Oliveira MA, Santiago VF, Palmisano G, Barbosa CMV, Hebeda CB, Farsky SHP, Monteiro G. Influence of lysosomal protease sensitivity in the immunogenicity of the antitumor biopharmaceutical asparaginase. Biochem Pharmacol. 2020 Dec;182:114230. doi: 10.1016/j.bcp.2020.114230. Epub 2020 Sep 23. PMID: 32979352.

Gavinho B, Sabatke B, Feijoli V, Rossi IV, da Silva JM, Evans-Osses I, Palmisano G, Lange S, Ramirez MI. Peptidylarginine Deiminase Inhibition Abolishes the Production of Large Extracellular Vesicles From Giardia intestinalis, Affecting Host-Pathogen Interactions by Hindering Adhesion to Host Cells. Front Cell Infect Microbiol. 2020 Sep 23;10:417. doi: 10.3389/fcimb.2020.00417. PMID: 33072615; PMCID: PMC7539837.

Macedo-da-Silva J, Marinho CRF, Palmisano G, Rosa-Fernandes L. Lights and Shadows of TORCH Infection Proteomics. Genes (Basel). 2020 Aug 5;11(8):894. doi: 10.3390/genes11080894. PMID: 32764347; PMCID: PMC7464470.

Brian Effer, Eduardo Krebs Kleingesinds, Guilherme Meira Lima, Iris Munhoz Costa, Ignacio Sánchez-Moguel, Adalberto Pessoa, Verônica Feijoli Santiago, Giuseppe Palmisano, Jorge G. Farías, Gisele Monteiro, Glycosylation of Erwinase results in active protein less recognized by antibodies,
Biochemical Engineering Journal,
https://doi.org/10.1016/j.bej.2020.107750.

Mule SN, Saad JS, Fernandes LR, Stolf BS, Cortez M, Palmisano G. Protein glycosylation in Leishmania spp. Mol Omics. 2020 Oct 12;16(5):407-424. doi: 10.1039/d0mo00043d. PMID: 32724945.

Rosa-Fernandes L, Barbosa RH, Dos Santos MLB, Angeli CB, Silva TP, Melo RCN, de Oliveira GS, Lemos B, Van Eyk JE, Larsen MR, Cardoso CA, Palmisano G. Cellular Imprinting Proteomics Assay: A Novel Method for Detection of Neural and Ocular Disorders Applied to Congenital Zika Virus Syndrome. J Proteome Res. 2020 Nov 6;19(11):4496-4515. doi: 10.1021/acs.jproteome.0c00320. Epub 2020 Aug 4. PMID: 32686424; PMCID: PMC7640952.

Guilherme Meira Lima, Brian Effer, Henrique Pellin Biasoto, Veronica Feijoli, Adalberto Pessoa, Giuseppe Palmisano, Gisele Monteiro, Glycosylation of L-asparaginase from E. coli through yeast expression and site-directed mutagenesis, Biochemical Engineering Journal, Volume 156, 2020, 107516, ISSN 1369-703X, https://doi.org/10.1016/j.bej.2020.107516.

Reis AS, Barboza R, Murillo O, Barateiro A, Peixoto EPM, Lima FA, Gomes VM, Dombrowski JG, Leal VNC, Araujo F, Bandeira CL, Araujo RBD, Neres R, Souza RM, Costa FTM, Pontillo A, Bevilacqua E, Wrenger C, Wunderlich G, Palmisano G, Labriola L, Bortoluci KR, Penha-Gonçalves C, Gonçalves LA, Epiphanio S, Marinho CRF. Inflammasome activation and IL-1 signaling during placental malaria induce poor pregnancy outcomes. Sci Adv. 2020 Mar 4;6(10):eaax6346. doi: 10.1126/sciadv.aax6346. PMID: 32181339; PMCID: PMC7056302.

New insights into Trypanosoma cruzi evolution and genotyping based on system-wide protein expression profiles (PhyloQuant)

Simon Ngao Mule, Andrè Guillherme da Costa Martins, Livia Rosa-Fernandes, Gilberto Santos de Oliveira, Carla Monadeli Rodrigues, Daniel Quina, Graziella E. Rosein, Marta Maria Geraldes Teixeira, Giuseppe Palmisano

bioRxiv 2020.02.21.959767; doi: https://doi.org/10.1101/2020.02.21.959767

2019

Barbosa RH, Dos Santos MLB, Silva TP, Rosa-Fernandes L, Pinto AMV, Spínola PS, Bonvicino CR, Fernandes PV, Lucena E, Palmisano G, Melo RCN, Cardoso CAA, Lemos B. Impression Cytology Is a Non-invasive and Effective Method for Ocular Cell Retrieval of Zika Infected Babies: Perspectives in OMIC Studies. Front Mol Neurosci. 2019 Dec 5;12:279. doi: 10.3389/fnmol.2019.00279. PMID: 31866819; PMCID: PMC6907025.

Meneguetti GP, Santos JHPM, Obreque KMT, Barbosa CMV, Monteiro G, Farsky SHP, de Oliveira AM, Angeli CB, Palmisano G, Ventura SPM, Pessoa-Junior A, Rangel-Yagui CO. Correction: Novel site-specific PEGylated L-asparaginase. PLoS One. 2019 Oct 24;14(10):e0224592. doi: 10.1371/journal.pone.0224592. Erratum for: PLoS One. 2019 Feb 12;14(2):e0211951. PMID: 31648262; PMCID: PMC6812816.

Kawahara R, Recuero S, Nogueira FCS, Domont GB, Leite KRM, Srougi M, Thaysen-Andersen M, Palmisano G. Tissue Proteome Signatures Associated with Five Grades of Prostate Cancer and Benign Prostatic Hyperplasia. Proteomics. 2019 Nov;19(21-22):e1900174. doi: 10.1002/pmic.201900174. Epub 2019 Oct 20. PMID: 31576646.

Chatterjee S, Lee LY, Kawahara R, Abrahams JL, Adamczyk B, Anugraham M, Ashwood C, Sumer-Bayraktar Z, Briggs MT, Chik JHL, Everest-Dass A, Förster S, Hinneburg H, Leite KRM, Loke I, Möginger U, Moh ESX, Nakano M, Recuero S, Sethi MK, Srougi M, Stavenhagen K, Venkatakrishnan V, Wongtrakul-Kish K, Diestel S, Hoffmann P, Karlsson NG, Kolarich D, Molloy MP, Muders MH, Oehler MK, Packer NH, Palmisano G, Thaysen-Andersen M. Protein Paucimannosylation Is an Enriched N-Glycosylation Signature of Human Cancers. Proteomics. 2019 Nov;19(21-22):e1900010. doi: 10.1002/pmic.201900010. Epub 2019 Oct 16. PMID: 31419058.

Capelli-Peixoto J, Mule SN, Tano FT, Palmisano G, Stolf BS. Proteomics and Leishmaniasis: Potential Clinical Applications. Proteomics Clin Appl. 2019 Nov;13(6):e1800136. doi: 10.1002/prca.201800136. Epub 2019 Aug 26. PMID: 31347770.

CImP: Cellular Imprinting Proteomics applied to ocular disorders elicited by Congenital Zika virus Syndrome

Livia Rosa-Fernandes, Raquel Hora Barbosa, Maria Luiza B. dos Santos, Claudia B. Angeli, Thiago P. Silva, Rossana C. N. Melo, Gilberto Santos de Oliveira, Bernardo Lemos, Martin R. Larsen, Claudete Araujo Cardoso, Giuseppe Palmisano

bioRxiv 648600; doi: https://doi.org/10.1101/648600

Terra LF, Wailemann RAM, Dos Santos AF, Gomes VM, Silva RP, Laporte A, Meotti FC, Terra WR, Palmisano G, Lortz S, Labriola L. Heat shock protein B1 is a key mediator of prolactin-induced beta-cell cytoprotection against oxidative stress. Free Radic Biol Med. 2019 Apr;134:394-405. doi: 10.1016/j.freeradbiomed.2019.01.023. Epub 2019 Jan 27. PMID: 30699366.

Fonseca LD, Eler JP, Pereira MA, Rosa AF, Alexandre PA, Moncau CT, Salvato F, Rosa-Fernandes L, Palmisano G, Ferraz JBS, Fukumasu H. Liver proteomics unravel the metabolic pathways related to Feed Efficiency in beef cattle. Sci Rep. 2019 Mar 29;9(1):5364. doi: 10.1038/s41598-019-41813-x. PMID: 30926873; PMCID: PMC6441086.

Rosa-Fernandes L, Cugola FR, Russo FB, Kawahara R, de Melo Freire CC, Leite PEC, Bassi Stern AC, Angeli CB, de Oliveira DBL, Melo SR, Zanotto PMA, Durigon EL, Larsen MR, Beltrão-Braga PCB, Palmisano G. Zika Virus Impairs Neurogenesis and Synaptogenesis Pathways in Human Neural Stem Cells and Neurons. Front Cell Neurosci. 2019 Mar 15;13:64. doi: 10.3389/fncel.2019.00064. PMID: 30949028; PMCID: PMC6436085.

Simultaneous proteomics and three PTMomics characterization of pro-inflammatory cytokines stimulated INS-1E cells using TiO₂ enrichment strategy

Honggang Huang, Lylia Drici, Pernille S. Lassen, Giuseppe Palmisano, Martin R. Larsen

bioRxiv 509125; doi: https://doi.org/10.1101/509125

2018

Carregari VC, Rosa-Fernandes L, Baldasso P, Bydlowski SP, Marangoni S, Larsen MR, Palmisano G. Author Correction: Snake Venom Extracellular vesicles (SVEVs) reveal wide molecular and functional proteome diversity. Sci Rep. 2018 Oct 23;8(1):15908. doi: 10.1038/s41598-018-33284-3. Erratum for: Sci Rep. 2018 Aug 13;8(1):12067. PMID: 30349050; PMCID: PMC6198013.

Kawahara R, Rosa-Fernandes L, Dos Santos AF, Bandeira CL, Dombrowski JG, Souza RM, Da Fonseca MP, Festuccia WT, Labriola L, Larsen MR, Marinho CRF, Palmisano G. Integrated Proteomics Reveals Apoptosis-related Mechanisms Associated with Placental Malaria. Mol Cell Proteomics. 2019 Feb;18(2):182-199. doi: 10.1074/mcp.RA118.000907. Epub 2018 Sep 21. PMID: 30242111; PMCID: PMC6356084.

Kawahara R, Ortega F, Rosa-Fernandes L, Guimarães V, Quina D, Nahas W, Schwämmle V, Srougi M, Leite KRM, Thaysen-Andersen M, Larsen MR, Palmisano G. Distinct urinary glycoprotein signatures in prostate cancer patients. Oncotarget. 2018 Sep 4;9(69):33077-33097. doi: 10.18632/oncotarget.26005. PMID: 30237853; PMCID: PMC6145689.

Avila CC, Mule SN, Rosa-Fernandes L, Viner R, Barisón MJ, Costa-Martins AG, Oliveira GS, Teixeira MMG, Marinho CRF, Silber AM, Palmisano G. Proteome-Wide Analysis of Trypanosoma cruzi Exponential and Stationary Growth Phases Reveals a Subcellular Compartment-Specific Regulation. Genes (Basel). 2018 Aug 15;9(8):413. doi: 10.3390/genes9080413. PMID: 30111733; PMCID: PMC6115888.

Carregari VC, Rosa-Fernandes L, Baldasso P, Bydlowski SP, Marangoni S, Larsen MR, Palmisano G. Snake Venom Extracellular vesicles (SVEVs) reveal wide molecular and functional proteome diversity. Sci Rep. 2018 Aug 13;8(1):12067. doi: 10.1038/s41598-018-30578-4. Erratum in: Sci Rep. 2018 Oct 23;8(1):15908. PMID: 30104604; PMCID: PMC6089973.

Freire CCM, Palmisano G, Braconi CT, Cugola FR, Russo FB, Beltrão-Braga PC, Iamarino A, Lima Neto DF, Sall AA, Rosa-Fernandes L, Larsen MR, Zanotto PMA. NS1 codon usage adaptation to humans in pandemic Zika virus. Mem Inst Oswaldo Cruz. 2018 May 10;113(5):e170385. doi: 10.1590/0074-02760170385. PMID: 29768530; PMCID: PMC5942634.

de Oliveira, G. S.; Kawahara, R.; Rosa-Fernandes, L.; et al. Development of a Trypanosoma cruzi strain typing assay using MS2 peptide spectral libraries (Tc-STAMS2). PLoS Negl Trop Dis Volume: 12 Issue: 4 Pages: e0006351. 2018

Freire, C. C. M.; Palmisano, G.; Braconi, C. T.; et al. NS1 codon usage adaptation to humans in pandemic Zika virus. Mem Inst Oswaldo Cruz Volume: 113 Issue: 5 Pages: e170385. 2018

Ramirez, Marcel I.; Amorim, Maria G.; Gadelha, Catarina; et al. Technical challenges of working with extracellular vesicles. Nanoscale. Volume: 10 Issue: 3. Pages: 881-906. 2018

2017

Fernandes, Lívia Rosa; Stern, Ana Carolina Bassi; de Cássia Cavaglieri, Rita; et al. 7-Ketocholesterol overcomes drug resistance in chronic myeloid leukemia cell lines beyond MDR1 mechanism. J Proteomics Volume: 151 Pages: 12-23. 2017

Rosa-Fernandes, Livia; Rocha, Victoria Bombarda; Carregari, Victor Corasolla; et al. A Perspective on Extracellular Vesicles Proteomics. Frontiers in Chemistry. Volume: 5. 2017
Esteves, Eliane; Maruyama, Sandra R.; Kawahara, Rebeca; et al. Analysis of the Salivary Gland Transcriptome of Unfed and Partially Fed Amblyomma sculptum Ticks and Descriptive Proteome of the Saliva. Frontiers in Cellular and Infection Microbiology Volume: 2017

Alves, Maria Julia Manso; Kawahara, Rebeca; Viner, Rosa; et al. Comprehensive glycoprofiling of the epimastigote and trypomastigote stages of Trypanosoma cruzi. J Proteomics Volume: 151 Pages: 182-192. 2017

Rosa-Fernandes, Livia; Maselli, Luciana M. P.; Maeda, Nair Y.; et al. Outside-in, inside-out: Proteomic analysis of endothelial stress mediated by 7-ketocholesterol. Chemistry and Physics of Lipids Volume: 207 Pages: 231-238. 2017

de Rezende, Eloiza; Kawahara, Rebeca; Pena, Mauricio S.; et al. Quantitative proteomic analysis of amastigotes from Leishmania (L.) amazonensis LV79 and PH8 strains reveals molecular traits associated with the virulence phenotype. Plos Neglected Tropical Diseases Volume: 11 Issue: 11. 2017

PIMENTEL, ANDRÉ C.; FUZITA, FELIPE J.; Palmisano, Giuseppe; FERREIRA, CLÉLIA; TERRA, WALTER R. Role of cathepsins D in the midgut of Dysdercus peruvianus. Comparative Biochemistry and Physiology. Part B: Biochemistry & Molecular Biology (Print) JCR, v. 204, p. 45-52, 2017.

2016

Gilberto Santos de Oliveira; Rebeca Kawahara; Livia Rosa-Fernandes; Carla C. Avila; Martin R. Larsen; João Marcelo Pereira Alves; Giuseppe Palmisano. Novel DNA coding regions and protein arginylation reveal unexplored T.cruzi proteome and PTMs. International Journal of Mass Spectrometry, Accept 2016.

AVILA, C. C.; ALMEIDA, F. G.; PALMISANO, G. Direct identification of trypanosomatids by matrix-assisted laser desorption ionization-time of flight mass spectrometry (DIT MALDI-TOF MS). Journal of Mass Spectrometry (Print) JCR, v. 51, p. 549-557, 2016.

BOYSEN, ANDERS; Palmisano, Giuseppe; KROGH, THØGER JENSEN; DUGGIN, IAIN G; LARSEN, MARTIN R.; MØLLER-JENSEN, JAKOB. A novel mass spectrometric strategy -BEMAP- reveals Extensive O-linked protein glycosylation in Enterotoxigenic Escherichia coli. Scientific Reports JCR, v. 6, p. 32016, 2016.

FERNANDES, LÍVIA ROSA; STERN, ANA CAROLINA BASSI; DE CÁSSIA CAVAGLIERI, RITA; NOGUEIRA, FÁBIO CÉSAR SOUSA; DOMONT, GILBERTO; Palmisano, Giuseppe; BYDLOWSKI, SÉRGIO PAULO. 7-Ketocholesterol overcomes drug resistance in Chronic Myeloid Leukemia cell lines beyond MDR1 mechanism. Journal of Proteomics (Print) JCR, v. 1, p. 1, 2016.

ALVES, MARIA JULIA MANSO; KAWAHARA, REBECA; VINER, ROSA; COLLI, WALTER; MATTOS, ELICIANE CEVOLANI; THAYSEN-ANDERSEN, MORTEN; LARSEN, MARTIN RØSSEL; Palmisano, Giuseppe. Comprehensive glycoprofiling of the epimastigote and trypomastigote stages of Trypanosoma cruzi. Journal of Proteomics (Print) JCR, v. 1, p. 1, 2016.

HUANG, HONGGANG ; HAAR PETERSEN, MARTIN; IBAÑEZ-VEA, MARIA; LASSEN, PERNILLE S.; LARSEN, MARTIN R.; Palmisano, Giuseppe. Simultaneous Enrichment of Cysteine-containing Peptides and Phosphopeptides Using a Cysteine-specific Phosphonate Adaptable Tag (CysPAT) in Combination with titanium dioxide (TiO ) Chromatography. Molecular & Cellular Proteomics JCR, v. 15, p. 3282-3296, 2016.

2015

MILIOLI, MARCO; IBÁÑEZ-VEA, MARIA; SIDOLI, SIMONE; Palmisano, Giuseppe; CARERI, MARIA; LARSEN, MARTIN R. Quantitative proteomics analysis of platelet-derived microparticles reveals distinct protein signatures when stimulated by different physiological agonists. Journal of Proteomics (Print) JCR, v. 121, p. 56-66, 2015.

YANG, FEN; LI, WANSHUN; DERBYSHIRE, MARK; LARSEN, MARTIN R; RUDD, JASON J; Palmisano, Giuseppe. Unraveling incompatibility between wheat and the fungal pathogen Zymoseptoria tritici through apoplastic proteomics. BMC Genomics JCR, v. 16, p. 362, 2015.

GABRIEL, HELOISA B.; DE AZEVEDO, MAURO F.; Palmisano, Giuseppe; WUNDERLICH, GERHARD; KIMURA, EMÍLIA A.; KATZIN, ALEJANDRO M; ALVES, JOÃO M. P. Single-target high-throughput transcription analyses reveal high levels of alternative splicing present in the FPPS/GGPPS from Plasmodium falciparum. Scientific Reports JCR, v. 5, p. 18429, 2015.

LI, HAIYING; RASMUSSEN, MORTEN I; LARSEN, MARTIN R; GUO, YAO; JERS, CARSTEN; Palmisano, Giuseppe; MIKKELSEN, JØRN D; KIRPEKAR, FINN. Automated -glycan profiling of a mutant sialidase expressed in, using tandem mass spectrometry and bioinformatics. Glycobiology (Oxford) JCR, v. 25, p. 1350-1361, 2015.

2014

MELO-BRAGA, M. N.; SCHULZ, M.; LIU, Q.; SWISTOWSKI, A.; PALMISANO, G.; ENGHOLM-KELLER, K.; JAKOBSEN, L.; ZENG, X.; LARSEN, M. R. Comprehensive Quantitative Comparison of the Membrane Proteome, Phosphoproteome, and Sialiome of Human Embryonic and Neural Stem Cells. Molecular & Cellular Proteomics JCR, v. 13, p. 311-328, 2014.

HUANG, HONGGANG; LARSEN, MARTIN R.; Palmisano, Giuseppe; DAI, JIE; LAMETSCH, RENÉ. Quantitative phosphoproteomic analysis of porcine muscle within 24h postmortem. Journal of Proteomics (Print) JCR, v. 106, p. 125-139, 2014.

Laboratório de GlicoProteômica

Instituto de Ciências Biomédicas

Departamento de Parasitologia