Neuromodulation
Focused ultrasound provides spatial resolution and dedicated ultrasonic energy for neuromodulation, offering a non-invasive and precise approach to stimulate specific areas of the brain. The ultrasound neuromodulation technique has shown potential applications in the treatment of neurological disorders such as Parkinson’s and depression, avoiding invasive surgeries and minimizing associated risks.
Additionally, focused ultrasound has garnered attention for its ability to enhance drug delivery to the brain, known as focused ultrasound-mediated blood-brain barrier (BBB) disruption. This innovative technique allows for temporary and localized permeabilization of the BBB, facilitating the passage of therapeutic agents into the brain tissue. By combining focused ultrasound with drug delivery, researchers aim to improve the effectiveness of treatments for various neurological conditions.
Furthermore, the versatility of focused ultrasound extends beyond neuromodulation and drug delivery. It has also been explored for its potential role in sonothrombolysis, a non-invasive method for breaking down blood clots in the brain’s vasculature. This application holds promise for addressing conditions such as ischemic stroke.
As research in the field of focused ultrasound continues to advance, its diverse applications underscore its potential to revolutionize the landscape of neurotherapeutics, providing safer and more targeted interventions for a range of neurological challenges.
Read More at:
- KAMIMURA, H.A.S. – Multifrequency excitation and safety aspects for transcranial sonothrombolysis – (PhD Dissertation – Graduate Program in Applied Physics to Medicine and Biology) – Faculty of Philosophy, Sciences, and Letters of Ribeirão Preto, University of São Paulo. Ribeirão Preto – SP, 2016.Optimization of block matching algorithm applied to studies elastográficos
- KAMIMURA, H. et al – Ipsi- and contralateral motor response using ultrasound-induced neurostimulation in deeply anesthetized mice. Physics Procedia, 70, n. C, p. 1214-1217, 2015
- FusFoundation
Mateus Valença
Undergraduation Student
Victor Malheiro
Master Student