Beatriz Bezerra de Macedo
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Carolina Gimenes Oliveira
Background: Bachelor’s degree in Medical Physics and Master of Science from the Physics Department of the Faculty of Philosophy, Sciences and Languages of Ribeirão Preto, University of São Paulo (FFCLRP/USP). She is currently a PhD candidate in the Postgraduate Program in Physics Applied to Medicine and Biology (FAMB) at the same institution, under the supervision of Prof. Dr. Antonio José da Costa-Filho and co-supervision of Prof. Dr. Luis Felipe Santos Mendes. Her research focuses on molecular biophysics, intrinsically disordered proteins, and biomolecular condensates, with an emphasis on how post-translational modifications regulate condensate formation and physicochemical properties. (More information at: http://lattes.cnpq.br/257925613561355)
Research Project: Biophysical mechanisms of biomolecular condensation modulated by N-terminal acetylation. This PhD project investigates how post-translational modifications alter the conformational ensemble, phase behavior, structural organization, and ageing of condensates formed by the Golgi protein Grh1 and its acetylated variant. The work integrates multiple experimental approaches, including fluorescence microscopy, DLS, DSC, CD spectroscopy.
Contact: carolina.g.oliveira@usp.br (https://orcid.org/0000-0003-2560-9966)
Emanuel Kava
Background: Lic. Sc. in Physics from the Federal University of Paraná and MSc. degree from the Physics Department of the Faculty of Philosophy, Sciences and Languages of Ribeirão Preto/University of São Paulo (FFCLRP/USP). Currently he is a PhD student in the Postgraduate Program in Physics Applied to Medicine and Biology (FAMB) of the same Department. His academic training includes international research internships at the Institut Pasteur de Montevideo, University of Cambridge, and Leiden University, working in advanced bioimaging, membrane biophysics, and protein phase separation.
Research Project: Exploring the phase separation and membrane interaction of human Golgi Reassembly and Stacking Proteins (GRASPs).
This PhD project investigates how GRASP proteins form biomolecular condensates and interact with lipid membranes, combining fluorescence lifetime imaging (FLIM), hyperspectral imaging (HSI), electron spin resonance (ESR), and protein biochemistry. The goal is to understand the biophysical principles that underlie Golgi organization, unconventional protein secretion mediated by GRASPs and the role of myristoylation in modulating protein self-assembly and membrane association.
Contact: emanuelkava@usp.br (https://orcid.org/0000-0002-7216-2493)
Gabriel Machado de Oliveira
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