Departamento de Parasitologia – ICB

Departamento de Parasitologia

BEATRIZ SIMONSEN STOLF CARBONI

Phone: +55 (11) 3091-7266
Room: 121
Email: bstolf@usp.br
Currículo Lattes

Laboratory Leishmaniasis

GROUP MEMBERS

Eloiza de Rezende

Fabia T Tano

Janaina C Peixoto

Luiz Pereira da Silva

Karoline M. Leite

Mariana K. Galuppo

Maurício S. Peña

Patrizia Dardi

RESEARCH LINE

Study of proteins from Leishmania amazonensis and from itsmurine host involved in the success of infection by this parasite

The profile of the infection by Leishmania depends on parasite genetics and on characteristics of the host immune system. For this reason, our group is interested in parasite and host proteins involved in the infection process. We also analyze how murine immune system impacts the parasite proteome.
We study potential virulence factors of Leishmania amazonensis, analyzing their roles in infection, phagocytosis and macrophage activation. We also search for host cell ligands for some of these factors. We also analyze the role of macrophage CD100 in the infection by L.amazonensis.

PUBLICATIONS

Rezende, E, Sakuma, R, Palmisano, G, Stolf, BS. PLoS Negl Trop Dis. 2017 Nov 27;11(11):e0006090. doi: 10.1371/journal.pntd.0006090.

Peña MS, Cabral GC, Fotoran WL, Perez KR, Stolf BS.

Cell Death Dis. 2017 Mar 2;8(3):e2645. doi: 10.1038/cddis.2017.59.
Jornal da USP, maio de 2017: jornal.usp.br/ciencias/ciencias-biologicas/pesquisa-detecta-proteinas-que-podem-interferir-na-morte-da-leishmaniahttp://jornal.usp.br/ciencias/ciencias-biologicas/pesquisa-detecta-proteinas-que-podem-interferir-na-morte-da-leishmania

Velasquez, LG, Galuppo, MK,Rezende, E, Brandão, WN, Peron, JP, Uliana, SRB, Duarte, MI, Stolf, BS. Parasitology 2016, Feb 19; 1-12

Luque MC, Gutierrez PS, Debbas V, Kalil J, Stolf BS. Molecular Immunology. 2015 Oct;67(2 Pt B):559-67. doi: 10.1016/j.molimm.2015.07.028. Epub 2015 Aug 12

Teixeira, PC., Velasquez, LG., Lepique, AP., Rezende, E, Barcinski, MA., Cunha-Neto E., Stolf BS. PlosNTD. 2015, Feb 18;9

Luque, MCA., Gutierrez, PS., Debbas, V, Puech-Leao, P, Porto, G, Coelho, V, Boumsell, L, Kalil, J Stolf, BS. PlosOne 2013, v8 Issue 9, 1-9

Martins WK, Costa ÉT, Cruz MC, Stolf BS, Miotto R, Cordeiro RM, Baptista MS. Sci Rep. 2015 Jul 27;5:12425. doi: 10.1038/srep12425

Vania A. F. F. M. dos Santos, Karoline M. Leite, Mariana da Costa Siqueira, Luis O. Regasini, Isabel Martinez, Camila T. Nogueira, Mariana Kolos Galuppo, Beatriz S. Stolf, Regina M. B. Cicarelli, Maysa Furlan,Marcia A. S. Graminha. Molecules 2013 18(1): 1053-1062

Martins, W.K, Severino, D., Souza, C. Stolf, B.S., Baptista, M.S. Biotechnol. J. 2013, Jun;8(6):730-737

Stolf, BS, Ioannis, S, Lopes, LR,Goto, H, Laurindo, FRM, Shah, AM, Santos, CXC. The Scientific World Journal 2011, v. 11, p. 1749-1761

Porto, G, Ricardo, R.J., Marti, L.C., Stolf, B.S, Pasqualini, R., Arap, W., Kalil, J, Coelho, V. Plos One 2011 , 6(8)

Martins, WK, Esteves, GH, Almeida, OM, Rezze, GG, Landman, G, Marques, SM,Carvalho, AF, Reis, LFL, Duprat, JP, Stolf, BS. BMC Medical Genomics 2011, v. 4, p. 76

Andrade, C.R.; Stolf, B.S. ; Debbas, V. ; Rosa, D.S. ; Kalil, J. ; Coelho, V.; Laurindo, F.R.M. In Vitro Cellular & Developmental Biology. Animal (Print) 2011, v. s1162, p. 1-12

RESEARCH PROJECTS/FUNDING

FAPESP (2011/12634-9). Study of two molecules that potentially modulate infection of the macrophage by Leishmania amazonensis. 1/11/2011- 30/04/2014
PROCAD NF 21/2009- Building a network for the research of immunopathology of leishmaniasis. Coordinated by Fátima Ribeiro Dias

COLLABORATORS

  • Prof. Silvia Uliana - Dept of Parasitology | ICB-USP
  • Dr Carlos Robello- Institut Pasteur Montevideo
  • Prof. Giuseppe Palmisano, do Depto de Parasitologia | ICB-USP
  • Prof. Ricardo Giordano, do Depto de Bioquímica | IQ-USP
  • Prof. Maristela Camargo, do Depto de Imunologia | ICB-USP
  • Dra Yara Traub-Czenko, da Fiocruz do Rio de Janeiro
  • Prof. Albert Descoteaux da McGill University, Canadá
  • Dr Valeria Borges- Fiocruz Bahia